| 中文关键词: miRNA-30 卵巢癌 生物学标志物 化疗耐药 |
| 英文关键词:miRNA-30 ovarian cancer biological marker chemotherapy resistance |
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| 摘要点击次数: 1544 |
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| 中文摘要: |
| 摘 要：microRNAs (miRNAs) 是一类短链、非编码小分子miRNAs，通过调控重要的信号转导通路和相关癌基因参与肿瘤发生发展，侵袭转移和预后等生物过程。研究表明miRNA-30家族参与卵巢癌的发生、转移侵袭、介导铂耐药及预后过程。全文主要对miRNA-30家族在卵巢癌中作用研究进展作一综述。 |
| 英文摘要: |
| Abstract：MicroRNAs(miRNAs) are a group of short-chain，non-coding small RNAs that participate in the biological processes of tumorigenesis，invasion，metastasis，and prognosis by regulating important signal transduction pathways and related oncogenes. Studies have shown that the miRNA-30 family is involved in the carcinogenesis，metastasis，invasion，prognosis of ovarian cancer，and also in mediation of platinum sensitivity of chemotherapy. This review focuses on the research progress of the role of miRNA-30 family in ovarian cancer. |
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