| 刘 岩,任佳忠,杨国仁.分子影像技术在肿瘤细胞凋亡的研究现状及进展[J].肿瘤学杂志,2017,23(6):496-501. |
| 分子影像技术在肿瘤细胞凋亡的研究现状及进展 |
| Current Status and Advances on the Application of Molecular Imaging Techniques in Cancer Cell Apoptosis |
| 投稿时间：2016-12-01 |
| DOI：10.11735/j.issn.1671-170X.2017.06.B008 |
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| 中文关键词: 肿瘤细胞 细胞凋亡 分子影像探针 |
| 英文关键词:tumor cells apoptosis molecular imaging probe |
| 基金项目: |
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| 摘要点击次数: 1748 |
| 全文下载次数: 598 |
| 中文摘要: |
| 摘 要：细胞凋亡是由多种基因调控的主动性细胞死亡过程。通过放疗、化疗等手段诱导肿瘤细胞凋亡是各种抗肿瘤治疗的主要机制之一。分子影像学可以在细胞和分子水平上对活体内细胞凋亡的生物过程和某些疾病的发生机制进行定性、定量、实时监测。分子影像学技术主要包括PET、SPECT、MRI、超声成像、光学成像。全文主要对分子影像技术在肿瘤细胞凋亡的应用进行综述。 |
| 英文摘要: |
| Abstract：Apoptosis is a programmed cell death process involving a variety of gene regulation. To induce tumor cell apoptosis is one of the main mechanisms of antitumor therapy，including radiotherapy and chemotherapy. Cell apoptosis and biological process of diseases can be real-time，qualitatively and quantitatively monitored at the cellular and molecular level in the living body. The molecular imaging techniques include PET，SPECT，MRI，ultrasonic imaging and optical imaging. This article reviews the value of various molecular imaging techniques in monitoring of cancer cell apoptosis. |
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