杜瑀煊,柴可群,陈嘉斌.治疗结直肠癌复发转移的中药用药规律分析[J].肿瘤学杂志,2017,23(2):97-100. |
治疗结直肠癌复发转移的中药用药规律分析 |
Medicine Analysis of TCM in Treatment of Colon-rectal Cancer |
投稿时间:2016-11-20 |
DOI:10.11735/j.issn.1671-170X.2017.02.B004 |
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中文关键词: 肠肿瘤 中医传承辅助平台 数据挖掘 用药规律 |
英文关键词:colon-rectal neoplasms inheritance of traditional Chinese medicine software platform system data mining medication rule |
基金项目:浙江省中医药科学研究基金项目(2016ZB009) |
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中文摘要: |
摘 要:[目的] 分析预防治疗结直肠癌患者复发转移的中药的用药规律。[方法] 收集经病理诊断结直肠癌患者的中药处方321张,运用《中医传承辅助平台系统》(Ⅴ2.5)对数据进行用药规律挖掘,分析药物频次、关联规则和核心组合。[结果] 共纳入中药处方321张,涉及中药164味,用药频次3908次。使用频次最高的药物分别为甘草、太子参、茯苓、白术、半夏、当归、黄柏、薏苡仁、黄芩、肉桂。预防结直肠癌复发转移组的核心药对为太子参-白术-茯苓-甘草-黄柏-半夏-黄芩-肉桂。治疗结直肠癌复发转移组的核心药对为太子参-白术-茯苓-甘草-当归-黄芩-黄柏-苍术。[结论] 辨治结直肠癌多用补气健脾、温补肾阳、清热解毒、疏肝理气药物。 |
英文摘要: |
Abstract:[Objective] To investigate the major Chinese medicine rules in the treatment of patients with colon-rectal cancer. [Methods] The inheritance of traditional Chinese medicine software platform system were used to collect data,a total of 321 prescriptions from the patients with colon-rectal cancer proved pathologically were investigated. The drug frequency,association rule,core portfolio were analyzed. [Results] There were 321 prescriptions,including 164 herbs 3908 frequency. The most frequently herbs included licorice,pseudostellaria root,tuckahoe,atractylodes,pinellia,and so on. There were major core compositions,including radix pseudostellariae-licorice-cinnamon,pseudostellaria root-atractylodes poria cocos-licorice-cortex phellodendri-pinellia tuber and so on. [Conclusion] The major Chinese medicine treat for rectal cancer with radix pseudostellariae to rectum multi-purpose spleen,cassia twig to warming yang,Cortex phellodendri to eliminating phlegm and radix bupleuri to soothing the liver . |
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