| 邢培华,邵国良.125I粒子腔内治疗在中晚期胆管癌的临床应用进展[J].肿瘤学杂志,2016,22(11):951-956. |
| 125I粒子腔内治疗在中晚期胆管癌的临床应用进展 |
| 125I Seed Endovascular Treatment in the Application of Advanced Bile Duct Cancer |
| 投稿时间：2016-05-16 |
| DOI：10.11735/j.issn.1671-170X.2016.11.B016 |
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| 中文关键词: 胆管肿瘤 近距离放疗 125I粒子 |
| 英文关键词:cholangiocarcinoma brachytherapy 125I particles |
| 基金项目: |
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| 中文摘要: |
| 摘 要：胆管癌是指源于肝外胆管包括肝门区至胆总管下端胆管的恶性肿瘤，发病隐匿，发现肿瘤时大都已是中晚期，预后非常差，肿瘤引起的梗阻性黄疸等一系列并发症，使患者生活质量明显降低。姑息性治疗目前主要是经皮肝穿刺引流（PTCD）或内镜下胆道引流或支架植入，缓解患者的梗阻性黄疸征象，但随着肿瘤的进展，胆道再发梗阻发病率非常高。在胆道引流或支架基础上，行125I粒子腔内植入，在缓解梗阻基础上局部对肿瘤进行治疗，现就125I粒子腔内治疗在中晚期胆管癌的临床应用作一综述。 |
| 英文摘要: |
| Abstract：Cholangiocarcinoma refers from extrahepatic bile duct include hilar bile duct to the common bile duct cancer，with the incidence of occult.when it is found，tumor is already advanced，and might lose the opportunity of radical surgery. The prognosis is very poor. Due to obstruction caused by tumor jaundice and a series of complications，the patient survival time is short，and the quality is significantly reduced. At present，palliative treatment is percutaneous drainage(PTCD) or endoscopic biliary drainage or stent placement to alleviate the symptoms of obstructive jaundice，but with tumor progression，recurrence of biliary obstruction incidence rate is very high. Biliary drainage or stent，based on the line of 125I seed implantation cavity，within the line of local tumor irradiation therapy in relieving obstruction based on local treatment of tumors，in respect of 125I seeds endovascular treatment in the clinical application of advanced bile duct cancer are reviewed. |
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