| 解 鹏,尹 丽,郭业松.肺癌放疗计划中同层扫描与三相扫描的对比研究[J].肿瘤学杂志,2015,21(12):974-977. |
| 肺癌放疗计划中同层扫描与三相扫描的对比研究 |
| Comparison of Target-slice and Triphase CT Scan in the Radiation Therapy for Lung Cancer |
| 投稿时间：2015-06-17 |
| DOI：10.11735/j.issn.1671-170X.2015.12.B006 |
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| 中文关键词: 肺肿瘤 放射疗法 同层扫描 三相扫描 |
| 英文关键词:lung neoplasms radiation therapy target-slice scan triphase CT scan |
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| 中文摘要: |
| 摘 要：［目的］比较肺癌放疗中采取同层扫描及三相扫描时肿瘤靶区（GTV）体积、前后径、左右径、上下径及剂量体积直方图中双肺受量指标的差异。［方法］ 选取行放疗的肺癌患者10例，依次完成三相扫描及同层扫描，在相同的窗宽窗位上以相同的标准勾画靶区，将三相扫描获得的3套CT片中勾画的靶区融合后定义为GTV3x，将同层扫描获得的8套CT片中勾画的靶区融合后定义为GTV8x，分别制定Plan3x和Plan8x，比较GTV3x和GTV8x的体积、前后径、左右径、上下径及Plan3x和Plan8x双肺V5、V10、V20、V30的差别。［结果］ 两组相比，左右径、前后径无明显统计学差异（P值分别为0.167和0.575），体积、上下径有统计学差异（P值分别为0.005和0.001）。V5、、V10、V20、V30、MLD均有统计学差异（P值分别为0.003、0.005、0.000、0.002和0.000）。［结论］ 同层扫描相对于三相扫描，可降低双肺受量V5、V20、V30，在减轻放疗并发症、提高患者生活质量方面有优势。 |
| 英文摘要: |
| Abstract：［Purpose］ To compare the parameters of gross tumor volume，anteroposterior diameter，left-right diameter，vertical diameter and irradiation dose of the lungs in dose volume histograms between target-slice and triphase CT scan in the radiation therapy for lung cancer. ［Methods］ Ten patients of lung cancer receiving radiation therapy were analyzed. Target-slice and triphase CT scan of each patient were finished，respectively. Target volume was drawn in the same window width and window level. The target volume which fusing from three sets image of three-phase CT scan was defined as GTV3x，the target volume which fusing from eight sets image of triphase CT scan was defined as GTV8x，then Plan3x and Plan8x based on GTV3x and GTV8x were designed respectively. We compared the gross tumor volume，anteroposterior diameter，left-right diameter and vertical diameter. V5，V10，V20，V30，MLD of the lungs in dose volume histograms were also evaluated. ［Results］ There was no significant difference in anteroposterior diameter，left-right dia-meter between Plan3x and Plan8x(P=0.167，0.575). Gross tumor volume，Vertical diameter，V5，V10，V20，V30 and MLD in the Plan3x and Plan8x were significant different（P=0.005，0.001，0.003， 0.005，0.000，0.002，0.000）. ［Conclusion］ V5，V20，V30，MLD in Plan8x using target-slice CT scan reduce obviously in comparison with Plan3x using triphase CT scan. Furthermore，the radiation complications and the quality of life in patients may be improved. |
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