和倩倩,石 琨.抵抗素在胰岛素抵抗及肿瘤发生中的作用[J].肿瘤学杂志,2013,19(10):804-808.
抵抗素在胰岛素抵抗及肿瘤发生中的作用
The Role of Resistin in Insulin Resistance and Tumorigenesis
投稿时间:2013-04-25  
DOI:10.11735/j.issn.1671-170X.2013.10.B014
中文关键词:  抵抗素  胰岛素抵抗  肿瘤
英文关键词:resistin  insulin resistance  tumour
基金项目:
作者单位
和倩倩 哈尔滨医科大学附属第二医院 
石 琨 哈尔滨医科大学附属第二医院 
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中文摘要:
      摘 要:脂肪组织已经不是普通的脂肪储存仓库,近年的研究表明脂肪组织具有旺盛的内分泌功能。脂肪细胞分泌的众多脂肪因子当中,抵抗素是新近发现主要与胰岛素抵抗密切相关的脂肪因子,且与绒毛膜癌、子宫内膜癌、前列腺癌、结直肠癌、乳腺癌及胃癌的发生相关,在肿瘤发生、发展中起重要作用。
英文摘要:
      Abstract: The adipose tissue is increasingly viewed as not only an ordinary fat storage depot,but also an endocrine organ secreting various adipokines. Resistin is a member of the newly discovered family of adipokines. Previous studies have demonstrated that it has been closely associated with insulin resistance. Moreover,at present resistin is thought to be associated with choriocarcinoma,endometrial cancer,prostatic cancer,colorectal cancer,breast cancer and gastric cancer,which play an important role in the tumorigenesis and development.
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