| 王玲玲,王建清,常小红.华蟾素联合顺铂对非小细胞肺癌作用的研究进展[J].肿瘤学杂志,2013,19(10):758-761. |
| 华蟾素联合顺铂对非小细胞肺癌作用的研究进展 |
| Progress in Cinobutacini Combined with Cisplatin in the Treatment for Non-small Cell Lung Cancer |
| 投稿时间：2013-07-19 |
| DOI：10.11735/j.issn.1671-170X.2013.10.B004 |
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| 中文关键词: 华蟾素 化疗 顺铂 癌，非小细胞肺 |
| 英文关键词:cinobutacini chemotherapy cisplatin carcinoma,non-small cell lung |
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| 中文摘要: |
| 摘 要：肺癌是临床上最常见的恶性肿瘤之一，可通过手术、化疗、放疗等手段进行治疗，但是治愈率低，放疗及化疗的不良反应严重。顺铂是非小细胞肺癌的一线化疗药物。近年来发现，华蟾素具有抗肿瘤、减轻患者副作用、升高白细胞、提高患者免疫力的功效。对肝癌、胃癌、肺癌、乳腺癌、大肠癌、胆管癌、卵巢癌、人体胶质细胞瘤等的生长均有抑制作用及促进癌细胞凋亡的作用。本文旨在探讨一线化疗药物顺铂联合中药制剂华蟾素对肺癌治疗是否具有协同作用，从而延长患者生存率及改善生存质量。 |
| 英文摘要: |
| Abstract: Lung cancer is one of the most common malignant tumors. Surgery，chemotherapy，radiation therapy can be applied to ease some tumor，but the cure rate is low，and the side effects of radiotherapy and chemotherapy are severe. Cisplatin is first-line chemotherapeutic drug for non-small cell lung cancer. In recent years，it found that cinobutacini could inhibit tumor growth，reduce incidence of side effects，elevate white blood cells and improve immunity. For liver cancer，gastric cancer，lung cancer，breast cancer，colorectal cancer，bile duct carcinoma，ovarian cancer and human gliomas，cinobutacini can inhibit tumor growth and promote the role of the cancer cell apoptosis. This article aims to explore the efficacy of first-line chemotherapeutic drug combined with traditional Chinese medicine cinobutacini in the treatment for non-small cell lung cancer，in order to prolong survival and improve quality of life. |
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