| 刘菊英,问 静,郭业松.鼻咽腺样囊性癌临床分析[J].肿瘤学杂志,2012,18(12):927-929. |
| 鼻咽腺样囊性癌临床分析 |
| Clinical Analysis of Nasopharyngeal Adenoid Cystic Carcinoma |
| 投稿时间：2012-10-11 |
| DOI： |
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| 中文关键词: 鼻咽肿瘤 腺样囊腺癌 放射疗法 预后 |
| 英文关键词:nasopharyngeal neoplagms adenoid cystic carcinoma radiotherapy prognosis |
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| 中文摘要: |
| 摘 要：［目的］ 探讨鼻咽腺样囊性癌的临床特点及预后。［方法］ 回顾分析2000~2010年间收治的6例鼻咽腺样囊性癌，收集各项临床资料，随访其预后。［结果］ 病程最短为1个月，最长为36个月。6例均有颅底受累，4例海绵窦受侵，1例颈淋巴结转移（N1）。按鼻咽癌2008分期重新分期，5例Ⅳ期，1例Ⅲ期。所有病例放疗后评价疗效均为PR。4例局部复发，2例肺转移。［结论］ 鼻咽腺样囊性癌自然病程长，局部侵袭性强。放射治疗可延缓肿瘤发展，对部分病例仍可作为首选治疗手段。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the clinical features，treatment outcome and prognosis of patients with nasopharyngeal adenoid cystic carcinoma(ACC)．［Methods］ Six patients with ACC treated from 2001 to 2010 were reviewed retrospectively．Their clinical records were collected and the patients were follow-up. ［Results］ Among them，the shortest time from the first visit to clinical diagnosis was 1 months and the longest was 36 months．There were six cases with skull base involvement，4 cases with encroachment on cavernous sinus，1 case with cervical lymph node metastasis. According to the 2008 staging for nasopharyngeal carcinoma，5 patients restaged stage Ⅳ; 1，stage Ⅲ. All patients achieved PR after radiotherapy. Four cases had local recurrence and 2 cases had pulmonary metastases. ［Conclusion］ Nasopharyngeal ACC is a locally aggressive disease with a long natural course. Radiotherapy for nasopharyngeal ACC can prolong the time to progression，and may be used as the first choice. |
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