| 周胜利,顾 艳,袁 刚.螺旋CT灌注成像评估食管癌生物学行为的临床研究[J].肿瘤学杂志,2012,18(10):768-771. |
| 螺旋CT灌注成像评估食管癌生物学行为的临床研究 |
| A Clinical Trial of MSCT Perfusion Imaging in Evaluating Biological Behavior for Esophageal Cancer |
| 投稿时间：2012-06-18 |
| DOI： |
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| 中文关键词: 食管肿瘤 体层摄影术，X线计算机 灌注成像 |
| 英文关键词:esophageal neoplasms tomography,X-ray computed perfusion imaging |
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| 摘要点击次数: 1263 |
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| 中文摘要: |
| 摘 要：［目的］ 探讨螺旋CT（MSCT）灌注成像参数在食管癌生物学行为评估中的作用和价值。［方法］ 用MSCT对食管癌患者行灌注扫描，获得灌注参数值，再分别根据患者性别、肿瘤的组织学分型、解剖分段、浸润深度、分化程度及有无淋巴结转移等分成若干亚组，比较各组患者灌注参数值的差异。［结果］ 血流量(BF)值在侵及纤维膜组大于未侵及纤维膜组，两组差异具有统计学意义（Ｐ＜0.05）。表面通透性(PS)值在有淋巴结转移组大于无淋巴结转移组，两组差异有统计学意义（Ｐ＜0.05）。而患者性别、肿瘤的组织学分型、解剖分段、分化程度各组间的灌注参数差异均无统计学意义（Ｐ>0.05）。［结论］ MSCT灌注成像参数能够科学评估食管癌的生物学行为。BF值能够对癌组织食管壁浸润深度进行评估，PS值能够对是否发生淋巴结转移进行评估。 |
| 英文摘要: |
| Abstract: ［Purpose］ To discuss the role and value of spiral CT perfusion imaging parameters in evaluating the biological behavior for esophageal cancer．［Methods］ The perfusion parameters were obtained from patients who experienced the spiral CT scan，and the patients were divided into several subgroups according to gender，histologic type of tumor，invasive depth， differentiation of tumor cells and lymph node metastasis status. The difference of perfusion parameters between subgroups was analyzed. ［Results］ Blood flow（BF）in fibrous membrane invasion group was higher than that in group without fibrous membrane invasion， with significant difference（P＜0.05）. Besides，permeability surface(PS) in the group with lymph node metastasis was higher than that in group without lymph node metastasis， with significant difference（P＜0.05）. But no significant difference was observed on perfusion parameters between patients with genders，histologic types，anatomical classifications，or grades（P>0.05）. ［Conclusions］ Perfusion imaging parameters of the spiral CT are able to demonstrate biological behaviors for esophageal cancer. BF might be able to estimate the depth of tumor invasion，and PS might be able to assess lymph node metastasis status. |
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