崔永刚,廖栩鹤,王荣福.PET/CT 18F-FDG最大标准化摄取值对肺癌的诊断价值[J].肿瘤学杂志,2012,18(7):530-534. |
PET/CT 18F-FDG最大标准化摄取值对肺癌的诊断价值 |
The Value of the Maximum Standardized Uptake Value(SUVmax) of 18F-FDG PET/CT in the Diagnosis for Lung Cancer |
投稿时间:2012-06-06 |
DOI: |
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中文关键词: 肺肿瘤 PET/CT 标准化摄取值 18F-FDG 代谢显像 |
英文关键词:lung neoplasms PET/CT standardized uptake value 18F-FDG |
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中文摘要: |
摘 要:[目的]探讨肺部病灶18F-FDG PET/CT最大标准化摄取值(SUVmax)与病灶短径以及肺癌病理类型之间的相关性,以评估SUVmax诊断肺癌的价值。[方法]回顾性分析2010年7月至2012年2月127例行18F-FDG PET/CT显像的肺部占位患者,在PET/CT图像上测算肺部病灶的SUVmax值及最短径,并进行统计学分析。[结果]肺癌组和良性组的短径与SUVmax 之间分别均呈正相关;肺癌组与良性组的SUVmax存在统计学差异(P=0.0002),但两组短径无统计学差异(P=0.0938);鳞癌组与腺癌组的短径存在统计学差异(P=0.0059);非小细胞肺癌组和小细胞肺癌组之间的SUVmax及短径均无统计学差异(P=0.8932;P=0.6355)。[结论]18F-FDG PET/CT SUVmax可以作为肺部病灶良恶性诊断的有效指标,有助于肺部病灶的诊断和鉴别诊断。 |
英文摘要: |
Abstract:[Purpose] To evaluate the correlations of the maximum standardized uptake value (SUVmax) of 18F-FDG PET/CT and the short diameters of pulmonary lesions with the pathological types of lung cancer,and to assess the feasibility of using SUVmax as an important evaluation parameter for lung cancer diagnosis. [Methods] One hundred twenty-seven cases with clinically suspected lung cancer undergoing 18F-FDG PET/CT from July 2010 to February 2012,were retrospectively reviewed. All PET/CT images were analyzed visually and semiquantitatively by 2 physicians. In each case,the SUVmax and the short diameter of the lesions were calculated from the PET/CT images. All data were analyzed by statistical software. [Results] Positive correlation of the SUVmax and short diameter of the lesions in malignant group or benign group was found. A significant difference of SUVmax between malignant group and benign group was observed (P=0.0002),but not of the short diameters of the lesions (P=0.0938). The short diameter of squamous cell carcinoma group was significantly different from that of adenocarcinoma group(P=0.0059). However,there was no significant differences of SUVmax or short diameters between non-small cell lung cancer(NSCLC) group and small cell lung cancer group respectively(P=0.8932 and P=0.6355). [Conclusion] 18F-FDG PET/CT SUVmax might be used as an important parameter to differentiate malignant tumors from benign ones,contributing to the diagnosis and differential diagnosis for pulmonary lesions. |
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