| 李 靖,王玉峰,李思宇.2011—2020年金昌队列人群恶性肿瘤死亡率及早死概率研究[J].中国肿瘤,2021,30(12):905-910. |
| 2011—2020年金昌队列人群恶性肿瘤死亡率及早死概率研究 |
| Cancer Mortality and Probability of Premature Death in Jinchang Cohort，2011—2020 |
| 中文关键词 修订日期：2021-09-02 |
| DOI：10.11735/j.issn.1004-0242.2021.12.A005 |
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| 中文关键词: 金昌队列 恶性肿瘤 死亡率 早死概率 趋势 |
| 英文关键词:Jinchang Cohort malignant neoplasms mortality probability of premature death trend |
| 基金项目:校企合作项目（金科综2020-02） |
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| 中文摘要: |
| 摘 要：［目的］ 揭示金昌队列人群恶性肿瘤死亡率、早死概率及其变化趋势，确定肿瘤防治的高危人群和核心疾病，为健康干预提供重要依据。［方法］ 通过前瞻性研究，对金昌队列人群近10年的肿瘤死因随访，从人力资源部、退休管理中心、各二级单位工会、医保中心及医院获取死因数据，通过ID号构建用于分析恶性肿瘤死亡率和早死概率的数据库。［结果］ 2011—2020年金昌队列人群恶性肿瘤死亡率为252.19/10万，中国人口标化死亡率为131.18/10万。总人群恶性肿瘤死亡率前5位肿瘤依次为肺癌（88.83/10万）、胃癌（37.37/10万）、肝癌（30.43/10万）、食管癌（18.38/10万）、结直肠癌（17.56/10万）。男性恶性肿瘤死亡率前5位肿瘤依次为肺癌（125.36/10万）、胃癌（52.31/10万）、肝癌（41.79/10万）、食管癌（26.32/10万）、结直肠癌（23.03/10万）；女性恶性肿瘤死亡率前5位肿瘤依次为肺癌（29.07/10万）、胃癌（12.92/10万）、肝癌（11.84/10万）、结直肠癌（8.61/10万）、乳腺癌（8.07/10万）；男性、女性和总人群首位死因均为肺癌，在恶性肿瘤全死因中占比分别为37.35%、25.12%、35.22%。该人群近10年恶性肿瘤早死概率为6.39%，男性(2.76%)和女性(0.81%)恶性肿瘤早死概率首位均是肺癌。近10年该人群恶性肿瘤死亡率和早死概率变化趋势在男、女性和总人群中差异均无统计学意义。［结论］ 金昌队列人群恶性肿瘤死亡率前5位分别为肺癌、胃癌、肝癌、食管癌和结直肠癌，肺癌是导致男性和女性死亡的首位肿瘤，近10年恶性肿瘤死亡率和早死概率呈相对稳定状态。 |
| 英文摘要: |
| Abstract： ［Purpose］ To investigate the cancer mortality， the probability of premature death and their trends in the Jinchang Cohort. ［Methods］ This prospective study was based on a consecutive cohort(Jinchang Cohort) recruiting employees of Jinchang Group， a total of 489 717 person/year from 2011 to 2000 were included in the study. Data of death were obtained from the HR Office and hospitals of the Group， and the cancer mortality and the probability of premature death were analyzed. ［Results］ From 2011 to 2020， the crude mortality rate(CMR) of cancer in the Jinchang Cohort was 252.19/105， and age-standardized mortality rate(ASMR) was 131.18/105. The top 5 cancers with high mortality were lung cancer(88.83/105)， gastric cancer(37.37/105)， liver cancer(30.43/105)， esophageal cancer(18.38/105)， and colorectal cancer(17.56/105)； those in males were lung cancer(125.36/105)， gastric cancer(52.31/105)， liver cancer(41.79/105)， esophageal cancer(26.32/105)， and colorectal cancer(23.03/105)； and those in females were lung cancer(29.07/105)， gastric cancer(12.92/105)， liver cancer(11.84/105)， colorectal cancer(8.61/105)， and breast cancer(8.07/105). The leading cause of death among males， females and the total population was lung cancer， accounting for 37.35%， 25.12%， and 35.22% of all cancer deaths， respectively. From 2011 to 2020， the probability of premature death from cancer in Jinchang Cohort was 6.39%. And the premature death probability caused by lung cancer was 2.76% in males and 0.81% in females. There were no significant changes in cancer mortality and the premature death probability among males， females and total population during 2011 to 2020. ［Conclusion］ The cancers with top 5 mortality in the Jinchang Cohort were lung cancer， gastric cancer， liver cancer， esophageal cancer and colorectal cancer. Lung cancer was the leading cause of death among both males and females. The mortality and the probability of premature death have been relatively stable in the past decade. |
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