| 周海茸,洪 忻,周金意.2007—2019年南京市宫颈癌死亡与早死寿命损失年变化趋势分析[J].中国肿瘤,2021,30(9):683-688. |
| 2007—2019年南京市宫颈癌死亡与早死寿命损失年变化趋势分析 |
| Analysis on Trends of Cervical Cancer Mortality and Years of Life Lost from 2007 to 2019 in Nanjing |
| 中文关键词 修订日期：2021-01-21 |
| DOI：10.11735/j.issn.1004-0242.2021.09.A008 |
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| 中文关键词: 宫颈癌 死亡率 早死寿命损失年 江苏 |
| 英文关键词:cervical cancer mortality years of life lost Jiangsu |
| 基金项目:南京市卫生科技发展专项资金（ZKX18049） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2007—2019年南京市居民宫颈癌死亡特征及过早死亡寿命损失年（years of life lost，YLL）变化趋势。［方法］ 通过南京市全死因监测系统，收集2007年1月1日至2019年12月31日南京市户籍居民宫颈癌死亡病例。计算宫颈癌粗死亡率、中国人口标化死亡率（中标死亡率）、累积死亡率（0~74岁）、截缩死亡率（35~64岁）和YLL。中标率采用2000年全国第五次人口普查标准人口构成进行标化。应用Joinpoint回归分析宫颈癌死亡率、YLL率的变化趋势，计算年度变化百分比（annual percentage change，APC）和平均年度变化百分比（average annual percentage change，AAPC）。［结果］ 2007—2019年南京市宫颈癌死亡1178例，粗死亡率为2.81/10万，中标死亡率为1.40/10万，累积死亡率（0~74岁）为0.19%，截缩死亡率（35~64岁）为3.82/10万，中位死亡年龄为57岁；2007—2019年南京市宫颈癌粗死亡率、中标死亡率、累积死亡率（0~74岁）和截缩死亡率（35~64岁）均呈上升趋势（APC分别为7.50%、4.03%、5.18%、5.45%，P均＜0.05）。2007—2019年宫颈癌死亡率呈现双峰分布，50～岁组为第一个高峰，80～岁组为第二个高峰，年龄别死亡率随年龄的增长而上升（AAPC=7.50%，P＜0.05）。南京市宫颈癌粗死亡率和中标死亡率均为农村地区高于城市地区，且农村地区粗死亡率和中标死亡率均呈上升趋势（APC分别为7.90%、4.51%，P均＜0.05）。2007—2019年南京市宫颈癌平均YLL为2 843人年，粗YLL率呈显著上升趋势（APC=6.26%，P＜0.05）。［结论］ 南京市宫颈癌死亡率有明显年龄和城乡分布差异，提示可根据高危人群特征逐步推进早诊早治工作，减轻个人和社会的癌症负担。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the mortality and years of life lost(YLL) trends of cervical cancer from 2007 to 2019 in Nanjing. ［Methods］ Mortality rate， age-standardized mortality rate， cumulative rate(0~74 years-old) and truncated rate(35~64 years-old) of cervical cancer from 2007 to 2019 were calculated. The age-standardized mortality rate was calculated and adjusted by the Chinese standard population in 2000（ASMRC）. The annual percentage change(APC) and average annual percentage change(AAPC) of the mortality rate and YLL rate were analyzed by using Joinpoint regression analysis， and the trends in different age-groups were also analyzed. ［Results］ From 2007 to 2019， 1178 cases died of cervical cancer in Nanjing， the crude mortality rate was 2.81/105， the average ASMRC was 1.40/105， the cumulative rate(0~74 years-old) was 0.19% and the truncated rate(35~64 years-old) was 3.82/105. From 2007 to 2019， the crude mortality rate， age-standardized mortality rate， cumulative rate(0~74 years-old) and truncated rate(35~64 years-old) were increased with year(the APC was 7.50%， 4.03%， 3.86% and 5.45%， respectively； all P＜0.05). Two peaks of mortality rate were observed at the age group of 50 years and 80 years， and the age-specific mortality rate of cervical cancer increased with age from 2007 to 2019(the AAPC was 7.50%， P＜0.05). The crude mortality rate and ASMRC of cervical cancer in rural areas were higher than those in urban areas and increased with year(the APC was 7.90% and 4.51%， respectively； both P＜0.05). From 2007 to 2019， the average YLL was 2 843 person-year， and the crude YLL rate of cervical cancer increased with year(the APC was 6.26%； P＜0.05). ［Conclusion］ The mortality and YLL of cervical cancer in Nanjing present a increasing trend from 2007 to 2019， indicating that the screening and prevention strategies of cervical cancer should be strengthened. |
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