张 芹,潘恩春,武 鸣.2015年江苏省女性乳腺癌发病与死亡及2006—2015年趋势分析[J].中国肿瘤,2021,30(9):654-659.
2015年江苏省女性乳腺癌发病与死亡及2006—2015年趋势分析
Incidence and Mortality of Female Breast Cancer in 2015 and Trend from 2006 to 2015 in Jiangsu
中文关键词  修订日期:2021-03-03
DOI:10.11735/j.issn.1004-0242.2021.09.A003
中文关键词:  乳腺癌  女性  发病率  死亡率  趋势  江苏
英文关键词:breast cancer  female  incidence  mortality  trend  Jiangsu
基金项目:国家重点研发计划(2016YFC1302603) ;江苏省卫生计生委医学科研课题(H2017017);江苏省卫生计生委医学科研课题(H2017018)
作者单位
张 芹 淮安市疾病预防控制中心 
潘恩春 淮安市疾病预防控制中心 
武 鸣 江苏省疾病预防控制中心 
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中文摘要:
      摘 要:[目的] 分析2015年江苏省女性乳腺癌发病和死亡流行特征及2006—2015年间趋势变化。[方法] 从质控合格的2015年江苏省肿瘤登记数据中抽取女性乳腺癌病例,根据同期全省实际户籍人口,估算全省发病数、死亡数,分城乡、年龄别计算相应的发病粗率、死亡粗率、中国人口标化率(中标率)、世界人口标化率(世标率)、累积率(0~74岁)等指标。利用Joinpoint软件计算2006—2015年女性乳腺癌发病率、死亡率的平均年度变化百分比(AAPC)。[结果] 江苏省2015年女性乳腺癌估计新发14 641例患者,居女性发病癌谱第1位;发病粗率为38.83/10万,中标发病率和世标发病率分别为26.34/10万、24.71/10万,累积发病率(0~74岁)为2.65%,发病高峰在50~54岁年龄组。同期,估计全省女性乳腺癌死亡3 379例,位居女性死亡癌谱第6位;死亡粗率为8.96/10万,中标死亡率和世标死亡率分别为5.29/10万、5.14/10万,累积死亡率(0~74岁)为0.56%,死亡高峰在85+岁年龄组。2006—2015年江苏省女性乳腺癌发病率、死亡率及其中标率均呈明显上升趋势(P均<0.05)。女性乳腺癌发病水平AAPC农村地区高于城市地区。[结论] 乳腺癌是江苏省女性发病第1位的恶性肿瘤,2006—2015年其发病率、死亡率均呈明显上升趋势,应针对不同地区流行特征,加强对重点女性人群乳腺癌的预防和控制。
英文摘要:
      Abstract:[Purpose] To analyze the incidence, mortality of female breast cancer in 2015 in Jiangsu and trend of changes from 2006 to 2015. [Methods] Data of new cases and deaths of female breast cancer of 2015 in Jiangsu were collected and assessed for analysis. The new cases/deaths of female breast cancer in Jiangsu were estimated based on the registered population data. The crude incidence/mortality rates, age-standardized rates by Chinese standard population in 2000(ASR China), age-standardized rates by Segi’s world standard population(ASR world), cumulative incidence/mortality rates(0~74 years) by areas and ages were calculated. Joinpoint regression was performed to calculate the average annual percentage change(AAPC) from 2006 to 2015. [Results] It was estimated that a total of 14 641 female breast cancer cases were reported in Jiangsu in 2015, ranking the first of all female cancer incidence. The crude incidence rate was 38.83/105, ASR China and ASR world were 26.34/105 and 24.71/105, respectively. The cumulative incidence rate(0~74 years) was 2.65%. Incidence peaked at the age group of 50~54. Meanwhile, there were 3 379 deaths of female breast cancer estimated in Jiangsu in 2015, ranking the sixth of all female cancer deaths. The crude mortality rate was 8.96/105, ASR China and ASR world were 5.29/105 and 5.14/105, respectively. The cumulative mortality(0~74 years old) rate was 0.56%. Mortality peaked at the 85+ age group. The AAPC of crude and standardized incidence and mortality all showed an upward trend(P<0.05) in Jiangsu from 2006 to 2015. The AAPC of female breast cancer incidence in rural areas was higher than that in urban areas. [Conclusion] The female breast cancer incidence ranked the first of all female cancer incidence in 2015 in Jiangsu. During 2006 to 2015, the incidence and mortality of female breast cancer presented a rising trend. The effective prevention and control of female breast cancer should be strengthened for high risk population.
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