| 朱云峰,王 乐,沈永洲.1977—2018年浙江省海宁市结直肠癌流行趋势分析[J].中国肿瘤,2020,29(11):833-837. |
| 1977—2018年浙江省海宁市结直肠癌流行趋势分析 |
| Trend of Colorectal Cancer Incidence and Mortality in Haining City，Zhejiang Province from 1977 to 2018 |
| 中文关键词 修订日期：2019-11-20 |
| DOI：10.11735/j.issn.1004-0242.2020.11.A008 |
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| 中文关键词: 结直肠癌 发病率 死亡率 趋势 肿瘤登记 浙江 |
| 英文关键词:colorectal cancer incidence mortality trend cancer registry Zhejiang |
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| 中文摘要: |
| 摘 要：［目的］ 分析浙江省海宁市居民42年结直肠发病率与死亡率变化趋势及流行特征。［方法］ 根据海宁市肿瘤登记处提供的1977—2018年结直肠癌数据，计算结直肠癌发病率、死亡率，中国人口标化率（中标率）采用1982年全国标准人口构成计算，年度变化百分比（APC）及95%可信区间（95%CI）采用Joinpoint软件进行统计检验。［结果］ 1977—2018年海宁市结直肠癌新发病例共4543例，发病粗率为17.17/10万，结肠癌占比为53.0%；死亡病例共2320例，死亡粗率8.77/10万，结肠癌占比为54.1%，死亡/发病比为0.51∶1；1977—1990年和2005—2018年两个不同时期相比，结直肠癌发病粗率由9.37/10万上升至28.82/10万，上升了2.07倍，死亡粗率由5.80/10万上升至13.02/10万，上升了1.24倍，结肠癌占比由37.1%上升至58.1%。经标化后，女性结直肠癌发病率呈上升趋势（P<0.05），而男性维持稳定（P>0.05）；男女结肠癌死亡率均呈上升趋势（P<0.05），而直肠癌呈下降趋势（P<0.05）。［结论］ 海宁市结直肠癌发病率和死亡率总体上仍呈上升趋势，应继续加强结直肠癌早诊早治和预防控制工作。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the trend of incidence and mortality of colorectal cancer in Haining city from 1977 to 2018.［Methods］ By using the data from the cancer registry of Haining，the crude incidence and mortality of colorectal cancer were estimated. The age-standardized rate(ASR) was calculated by using the Chinese standard population in 1982，and the annual percentage change(APC) and 95% confidence interval(CI) were analyzed with Joinpoint software. ［Results］ From 1977 to 2018，a total of 4743 new cases and 2320 death cases of colorectal cancer were reported in Haining，and the crude incidence and mortality were 17.17/105 and 8.77/105，respectively. The mortality to incidence ratio was 0.51∶1. Colon cancer accounted for 53.0% of all new cases and 54.1% of death cases. Compared with the period of 1977—1990，there was an increase of the crude incidence，mortality and the proportion of colon cancer in the period of 2005—2018，from 9.37/105 to 28.82/105，5.80/105 to 13.02/105，and 37.1% to 58.1%，respectively. The ASR of female incidence increased over time(P<0.05) and male incidence was stable(P>0.05). The ASR of colon cancer mortality increased over time(P<0.05) while that of rectal cancer decreased(P<0.05).［Conclusion］ In Haining，the overall incidence and mortality of colorectal cancer are still increasing，and the colon cancer became predominant. Screening combined with more prevention strategies of colorectal cancer should be reinforced.. |
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