陈 赛,陈亚南,毛琦善.呼出气体挥发性有机化合物分析在肺癌诊疗中的研究进展[J].中国肿瘤,2019,28(2):132-136.
呼出气体挥发性有机化合物分析在肺癌诊疗中的研究进展
Advances on Exhaled Volatile Organic Compounds in Dia-gnosis of Lung Cancer
投稿时间:2018-10-07  
DOI:10.11735/j.issn.1004-0242.2019.02.A011
中文关键词:  呼出气体  肺肿瘤  呼出气体挥发性有机化合物
英文关键词:exhaled gas detection  lung neoplasms  volatile organic compounds
基金项目:
作者单位
陈 赛 青岛大学附属烟台毓璜顶医院 
陈亚南 青岛大学附属烟台毓璜顶医院 
毛琦善 青岛大学附属烟台毓璜顶医院 
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中文摘要:
      摘 要:大多数肺癌患者发现时已属晚期,失去了临床最佳治疗时机,该病的早发现、早诊断、早治疗是现今临床工作中的重点。随着临床肺癌检测手段的不断更新发展,呼出气体检测以快速、风险小、无创伤、可重复、可操作性成为一种有广泛前景的检测手段。本综述主要就肺癌患者呼出气体中的特征性呼出气体挥发性有机化合物进行归纳比较,阐述可能的机制,探讨呼出气体研究目前所存在的问题及研究前景。
英文摘要:
      Abstract:Most of lung cancer are discovered late and the optimal time for clinical treatment is lost. The early detection,early diagnosis and early treatment of lung cancer are the focus of clinical research. In recent years,the measurement of cancer-related volatile organic compounds in exhaled gas has become a promising clinical means for early detection of lung cancer,with advantages of rapid speed,low risk,non-invasiveness,repeatability and maneuverability. This review summarizes the characteristics of volatile organic compounds in exhaled gas of lung cancer,elaborates the possible mechanism,discuss the existing problems and the prospects of future application.
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