| 杨 军,李 贺,郑荣寿.2014年中国胰腺癌发病与死亡分析[J].中国肿瘤,2018,27(6):420-425. |
| 2014年中国胰腺癌发病与死亡分析 |
| Incidence and Mortality of Pancreatic Cancer in China，2014 |
| 投稿时间：2018-02-26 |
| DOI：10.11735/j.issn.1004-0242.2018.06.A004 |
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| 中文关键词: 胰腺肿瘤 肿瘤登记 发病率 死亡率 中国 |
| 英文关键词:pancreatic neoplasms cancer registry incidence mortality China |
| 基金项目:中国医学科学院医学与健康科技创新工程（2016-12M-2-004） |
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| 中文摘要: |
| 摘 要：［目的］ 估计2014 年我国胰腺癌的发病与死亡情况，为我国胰腺癌防控工作的有效开展提供基础信息。［方法］ 按照全国肿瘤登记中心制订的数据审核方法和评价标准，对2017年全国449个登记处上报的2014年胰腺癌发病和死亡数据进行质量评估。对入选的339个登记处数据按城乡、性别以及年龄分层，计算全国肿瘤登记地区人群2014年胰腺癌的发病率和死亡率，结合2014年全国人口数据估计中国2014年胰腺癌的发病和死亡情况。标化率采用2000年全国人口普查的人口构成和世界标准人口（Segi’s）构成。［结果］ 2014年 339个登记处共覆盖登记人口288 243 347人（城市地区144 061 915人，农村地区144 181 432人），胰腺癌MV%为39.23%，DCO%为3.81%，M/I为0.88。2014年全国胰腺癌发病人数约9.22万，发病率6.74/10万（男性7.45/10万，女性5.99/10万），中国人口标化率(中标率)为4.29/10万，世界人口标化率(世标率)为4.25/10万，累积率（0~74岁）为0.51%。城市地区发病率为7.96/10万，中标发病率4.74/10万，农村地区发病率为5.26/10万，中标发病率3.66/10万。2014年全国胰腺癌死亡人数约8.11万，死亡率5.93/10万（男性6.64/10万，女性5.18/10万），中标死亡率3.69/10万，世标死亡率3.67/10万，累积死亡率（0~74岁）为0.43%。城市地区死亡率为7.12/10万，中标死亡率4.14/10万。农村地区死亡率为4.48/10万，中标死亡率3.07/10万。我国胰腺癌发病率和死亡率在45岁前较低，此后随年龄增长迅速上升，并于80～岁达到高峰，城乡年龄别发病率与死亡率曲线相近。［结论］ 胰腺癌是威胁我国居民健康的主要高致命性癌症，发病和死亡分别位居恶性肿瘤的第10位和第6位，且其发病率和死亡率在不同年龄、性别及城乡地区存在明显差异。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence and mortality rates of pancreatic cancer with population-based cancer registration data in 2014 from National Central Cancer Registry(NCCR). ［Methods］ Based on the data quality criteria from NCCR，data of pancreatic cancer submitted from 449 registries were evaluated，among which those from 339 registries were qualified and accepted for final analysis. Incidence and mortality stratified by areas(urban/rural)，sex，age-group were analyzed. Chinese population census in 2000 and Segi’s population were used for age-standard incidence/mortality rates. ［Results］ Among 339 cancer registries covered a total population of 288 243 347(144 061 915 in urban areas and 144 181 432 in rural areas). There were about 92 200 new cases and 81 100 death cases of pancreatic cancer diagnosed in 2014. The morphology verified cases accounted for 39.23%，death certification only cases accounted for 3.81%，and mortality to incidence ratio was 0.88. The crude incidence rate of pancreatic cancer was 6.74/105(7.45/105 in males and 5.99/105 in females) and the age-standardized rate by Chinese population(ASR China) was 4.29/105 and that by world population(ASR world) was 4.25/105，with a cumulative incidence rate(0~74 years) of 0.51%. The crude incidence rate and ASR China of pancreatic cancer in urban areas were 7.96/105 and 4.74/105，whereas 5.26/105 and 3.66/105 in rural areas. The crude mortality rate of pancreatic cancer was 5.93/105(6.64/105 in males and 5.18/105 in females) and the ASR China was 3.69/105 and ASR world was 3.67/105，with a cumulative mortality rate(0~74 years) of 0.43%. The crude mortality rate of pancreatic cancer was 7.12/105 in urban areas and 4.48/105 in rural areas and ASR China were 4.14/105 and 3.07/105，respectively. The age-specific incidence and mortality of pancreatic cancer increased greatly after 45 years and peaked at 80~85 years. ［Conclusion］ Pancreatic cancer is one of the most fatal cancers，which threatens the health of Chinese people，especially for men and urban residents. In the future，preferable measurements should be carried out according to the characteristics among different population. |
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