| 杜义安,郭剑民.相关炎症因子在胃癌进展中的研究进展[J].中国肿瘤,2014,23(5):399-402. |
| 相关炎症因子在胃癌进展中的研究进展 |
| Research Progress in Relevant Inflammatory Factors of Advanced Gastric Cancer |
| 投稿时间：2014-01-20 |
| DOI：10.11735/j.issn.1004-0242.2014.05.A011 |
|
 |
| 中文关键词: 炎症因子 胃癌 肿瘤进展 |
| 英文关键词:inflammatory factors gastric cancer progress |
| 基金项目: |
|
| 摘要点击次数: 1877 |
| 全文下载次数: 1238 |
| 中文摘要: |
| 摘 要：胃癌的发生发展是多因素共同作用的结果，包括环境、生物和遗传因素等，促炎因子以及抗炎因子起着重要的作用。越来越多的研究报道了炎性因子与胃癌易感性存在着重要的联系。相关炎症因子以多种途径促进胃癌的进展，包括直接激活NF?鄄κB刺激肿瘤细胞、上调黏附因子及促进肿瘤周围血管再生，以上途径还可抑制机体免疫，促使肿瘤细胞进展和转移。目前的研究已经发现了许多炎症因子在胃癌的发生发展中起到了重要作用。 |
| 英文摘要: |
| Abstract：The occurrence and development of gastric cancer is the results of many factors，including environmental，biological and genetic factors. Pro-inflammatory cytokines and anti-inflammatory cytokines play an important roles in these processes. More and more studies report that there were important links between inflammatory cytokines and susceptibility to gastric cancer. Inflammatory factors promoted the progress of gastric cancer in a variety of ways，including direct activation of NF-κB stimulate cancer cells，increasing adhesion molecules and promoting the regeneration of blood vessels around the tumor. These pathways also inhibite the immunity，and cause the progression and metastasis of tumor cells. The current studies have found that many inflammatory cytokines play an important role in the occurrence and development of gastric cancer. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |