郭慧敏,孔为民.子宫内膜癌治疗后随访策略的研究进展[J].肿瘤学杂志,2022,28(7):533-538.
子宫内膜癌治疗后随访策略的研究进展
Research Progress on Follow-up Strategies After Endometrial Cancer Treatment
投稿时间:2022-03-12  
DOI:10.11735/j.issn.1671-170X.2022.07.B001
中文关键词:  子宫内膜癌  随访  体格检查  症状  肿瘤标志物  PET
英文关键词:endometrial cancer  follow-up  physical examination  symptoms  tumor markers  positron emission tomography
基金项目:
作者单位
郭慧敏 首都医科大学附属北京妇产医院 
孔为民 首都医科大学附属北京妇产医院 
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中文摘要:
      摘 要:子宫内膜癌的5年生存率可达81%,但仍存在肿瘤复发风险,有效的随访可尽早发现早期及局部复发,提高患者生存率。目前随访中重视患者体格检查及症状评估;利用肿瘤标志物动态变化监测子宫内膜癌复发效果存在争议;影像学方法中大多使用CT、PET,灵敏度和特异度较高,但费用昂贵。医院随访并不是唯一的随访方式,对于低危患者护士主导的电话随访结合定期体检可以作为一种补充方式;高频随访并未取得明显获益。目前临床随访方案主要遵循的指南在随访频率上基本一致,但在随访内容上仍有不同。全文对随访方案的时间与内容作一综述,并比较了当前的随访指南,以期为子宫内膜癌患者随访提供相关参考。
英文摘要:
      Abstract: Endometrial cancer is one of the major female reproductive tract malignant tumors with increasing incidence in recent years. The 5-year survival rate of endometrial cancer is relatively high, but there is still a risk of tumor recurrence. The early and local recurrence can be timely detected by effective follow-up, and the survival of patients can be improved. At present, physical examination and symptom evaluation are the main methods to find recurrence of endometrial cancer in follow-up, and using dynamic changes of tumor markers to monitor the recurrence is controversial. CT and PET are effective to detect recurrence with high sensitivity and specificity, although the cost is high. Apart from hospital follow-up, nurse-led telephone call combined with regular physical examination can be used as a supplementary method for low-risk patients. Frequent follow-up do not yield significant benefits, the follow-up frequency in current clinical follow-up protocols mainly follow the guidelines, but there are some variations in follow-up contents. In this article, the research progress of follow-up duration and follow-up content are reviewed, and the current follow-up guidelines are compared, to provide reference for follow-up of endometrial cancer patients.
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