黄 芳,李 颖,姜 达.肺鳞癌驱动基因及其靶向治疗的研究进展[J].肿瘤学杂志,2014,20(12):1035-1039.
肺鳞癌驱动基因及其靶向治疗的研究进展
Progress in Lung Squamous Carcinoma Drive Gene and Its Targeted Therapy
投稿时间:2014-02-12  
DOI:10.11735/j.issn.1671-170X.2014.12.B014
中文关键词:  肺肿瘤  鳞状细胞  驱动基因  靶向治疗
英文关键词:lung neoplasms  squamous cell  drive gene  targeted therapy
基金项目:
作者单位
黄 芳 河北医科大学第四医院 
李 颖 河北医科大学第四医院 
姜 达 河北医科大学第四医院 
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中文摘要:
      摘 要:应用分子靶向药物治疗晚期肺腺癌已逐渐成为当今临床研究的主流,其中EGFR基因突变患者可从靶向治疗中获益。肺鳞癌驱动基因的研究相对较少,近期多种检测技术对肺鳞癌标本进行基因检测,结果发现多数标本存在多个可测靶点,针对这些靶点已开发出一系列药物,其疗效仍待观察。
英文摘要:
      Abstract:Application of targeted therapy for advanced lung adenocarcinoma has gradually become the mainstream of the clinical research nowadays. Patients with EGFR mutation can benefit from it. Lung squamous carcinoma drive gene is relatively studied few. A variety of testing techniques for genetic testing lung squamous carcinoma specimens find that most of the specimens exist measurable targets. According to these targets it has developed a series of therapeutic drugs. However the effectiveness remains to be defined.
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