梁 忠,郭 良,赵坚强.284例腮腺癌的临床治疗分析[J].肿瘤学杂志,2013,19(6):466-469.
284例腮腺癌的临床治疗分析
Clinical Analysis of 284 Cases with Parotid Gland Carcinoma
投稿时间:2013-05-20  
DOI:10.11735/j.issn.1671-170X.2013.06.B012
中文关键词:  腮腺肿瘤  治疗  生存率  外科手术
英文关键词:parotid gland neoplasms  treatment  survival  surgery
基金项目:
作者单位
梁 忠 浙江省肿瘤医院 
郭 良 浙江省肿瘤医院 
赵坚强 浙江省肿瘤医院 
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中文摘要:
      摘 要:[目的] 探讨影响腮腺癌治疗效果及预后的因素。[方法] 回顾分析284例腮腺癌临床资料,分析性别、年龄、病理类型、临床分期及治疗方法等对5年、10年生存率的影响。[结果] 全组病例5年、10年生存率分别为73.2%、52.0%。单因素分析显示病理类型(P=0.03)、临床分期(P=0.00)、面神经是否受累(P=0.00)是腮腺癌生存的预后因素,年龄(P=0.08)、性别(P=0.06)对腮腺癌预后无显著影响。原发灶首次单纯手术与手术加术后放疗相比较生存率差异无统计学意义(P>0.05),但两组与再次手术及再次手术+放疗组比较生存率差异具有统计学意义(P<0.05)。[结论] 手术是治疗腮腺癌的主要手段,首次手术、临床分期、病理类型及面神经是否受累是影响腮腺癌治疗效果及预后的重要因素。
英文摘要:
      Abstract:[Purpose] To investigate the influence factors of the therapeutic efficacy and prognosis of parotid gland carcinoma. [Methods] Data of 284 cases with parotid gland carcinoma were analyzed retrospectively. The influences of gender,age,pathological types,clinical stages and therapeutic methods,etc. on 5- and 10-year survival rates of parotid gland carcinoma were analyzed. [Results] Of all the cases,the 5- and 10-year survival rates were 73.2% and 52.0%. Univariate analysis showed that pathological type(P=0.03),clinical stage(P=0.00),and facial nerve involvement (P=0.00) were prognostic factors for parotid gland carcinoma. Age(P=0.08) and gender(P=0.06) had no significant influence on prognosis of parotid gland carcinoma. Survival rate had no significant difference between patients initially treated with surgery alone and those with surgery plus postoperative radiotherapy for primary lesion(P>0.05),but survival rates of the patients in the two groups were significantly different with those of secondary treatment(P<0.05). [Conclusions] Surgery is the commonest treatment for parotid gland carcinoma. Initial surgery,clinical staging,pathological type and facial nerve involvement are important influencing factors for prognosis of parotid gland carcinoma.
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