| 孙 强,李小勇,沈 鹏,等.浙江省肿瘤登记地区卵巢癌2021年流行特征及2000—2021年趋势分析[J].肿瘤学杂志,2026,32(9):733-740. |
| 浙江省肿瘤登记地区卵巢癌2021年流行特征及2000—2021年趋势分析 |
| Incidence and Mortality of Ovarian Cancer in 2021 and Trends from 2000 to 2021 in Zhejiang Province Cancer Registration Areas |
| 投稿时间:2026-07-16 |
| DOI:10.11735/j.issn.1671-170X.2026.09.B004 |
|
 |
| 中文关键词: 卵巢肿瘤 发病率 死亡率 肿瘤登记 浙江 |
| 英文关键词:ovarian neoplasms incidence mortality cancer registration Zhejiang |
| 基金项目: |
|
| 摘要点击次数: 13 |
| 全文下载次数: 0 |
| 中文摘要: |
| 摘 要:[目的] 分析浙江省肿瘤登记地区2021年卵巢癌发病与死亡特征,以及2000—2021年变化趋势。 [方法] 基于浙江省肿瘤登记处报告的2000—2021年卵巢癌监测数据,描述卵巢癌发病与死亡的粗率、中国标准人口标化率(简称中标率)、世界标准人口标化率(简称世标率)等指标,其长期变化趋势采用Joinpoint回归模型进行拟合,估计平均年度变化百分比(average annual percentage change,AAPC)及其95%置信区间(confidence interval,CI)。[结果] 2021年浙江省肿瘤登记地区报告卵巢癌新发病例数1 004例,中标发病率为5.77/10万。同期卵巢癌死亡病例434例,中标死亡率为1.95/10万。农村地区中标发病率(6.36/10万)高于城市地区(5.42/10万),但中标死亡率(1.83/10万)低于城市地区(2.03/10万)。发病与死亡高峰分别出现在65~69岁年龄组(19.43/10万)和80~84岁年龄组(17.79/10万)。2000—2021年卵巢癌中标发病率总体变化趋势无统计学意义(P=0.218),而城乡趋势显著相反。城市地区中标发病率呈下降趋势 (AAPC=-1.55%,95%CI:-2.12%~-0.95%,P<0.001),农村地区则明显上升 (AAPC=3.70%,95%CI:2.49%~5.00%,P<0.001)。同期,卵巢癌中标死亡率总体呈上升趋势(AAPC=1.92%,95%CI:0.65%~3.29%,P=0.006),其中城市地区上升趋势明显 (AAPC=2.15%,95%CI:0.97%~3.41%,P=0.001),农村地区变化无统计学意义(P>0.05)。[结论] 浙江省卵巢癌的总体疾病负担低于全国平均水平,但存在显著的城乡差异。未来需在农村地区重点控制危险因素以遏制发病增长,同时在城市地区着力强化早筛早治以降低死亡风险。 |
| 英文摘要: |
| Abstract: [Purpose] To analyze the incidence and mortality of ovarian cancer in Zhejiang Province cancer registration areas in 2021 and their trends from 2000 to 2021. [Methods] Data on ovarian cancer (2000—2021) reported by Zhejiang Province cancer registries were collected. Crude rates, age-standardized incidence/mortality rates by Chinese standard population (ASIRC/ASMRC) and by world standard population (ASIRW/ASMRW) were calculated. Joinpoint regression was used to estimate the average annual percentage change (AAPC) and its 95% confidence interval (CI). [Results] In 2021, 1 004 new ovarian cancer cases were reported, with an ASIRC of 5.77/105; 434 deaths occurred, with an ASMRC of 1.95/105. The ASIRC in rural areas (6.36/105) was higher than that in urban areas (5.42/105), whereas the ASMRC in rural areas (1.83/105) was lower than that in urban areas (2.03/105). Incidence peaked in the age group of 65-69 years old (19.43/105), and mortality peaked in the age group 80-84 years old (17.79/105). From 2000 to 2021, the overall ASIRC showed no significant change (P=0.218), but urban-rural trends diverged significantly: urban ASIRC declined (AAPC=-1.55%, 95%CI: -2.12%--0.95%, P<0.001), while rural ASIRC increased markedly (AAPC=3.70%, 95%CI: 2.49%-5.00%, P<0.001). The overall ASMRC rose significantly (AAPC=1.92%, 95%CI: 0.65%-3.29%, P=0.006), driven mainly by urban areas (AAPC=2.15%, 95%CI: 0.97%-3.41%, P=0.001), whereas rural ASMRC did not change significantly(P>0.05). [Conclusion] The overall burden of ovarian cancer in Zhejiang Province is lower than the national average, but marked urban-rural disparities exist. Future efforts should focus on controlling risk factors in rural areas to curb the rising incidence, while strengthening early screening and treatment in urban areas to reduce mortality. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |