| 朱 军,王 芳,邓裕山,等.四川省阆中市2017—2023年食管癌内镜筛查结果分析[J].肿瘤学杂志,2026,32(7):539-546. |
| 四川省阆中市2017—2023年食管癌内镜筛查结果分析 |
| Analysis of Endoscopic Screening Results for Esophageal Cancer in Langzhong City， Sichuan Province from 2017 to 2023 |
| 投稿时间：2025-10-11 |
| DOI：10.11735/j.issn.1671-170X.2026.07.B003 |
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| 中文关键词: 食管肿瘤 肿瘤筛查 早诊早治 检出率 四川 |
| 英文关键词:esophageal neoplasms cancer screening early diagnosis and early treatment detection rate Sichuan |
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| 中文摘要: |
| 摘 要：［目的］ 分析2017—2023年四川省阆中市早诊早治项目食管癌内镜筛查结果，为高发区防治策略优化提供参考依据。［方法］ 采用整群抽样的方法，选取阆中市40~69岁常住居民进行内镜下碘染色，对可疑病变进行病理活检，分析筛查人群的病变检出率、早诊率，以及性别、年龄和时间分布特征。［结果］ 2017—2023年共筛查19 977人，男女比例1∶1.44，平均年龄为（56.26±7.56）岁。 胃镜病理活检率为35.18%（7 028/19 977）。检出食管低级别上皮内瘤变992人，检出率为4.97%（992/19 977）；阳性病例（高级别上皮内瘤变+早期癌+进展期癌）349人，检出率为1.75%（349/19 977）；早期病例（高级别上皮内瘤变+早期癌）316例，检出率为1.58%（316/19 977），早诊率为90.54%（316/349）。男性各级别病变（低级别上皮内瘤变、高级别上皮内瘤变、早期癌、进展期癌）检出率均高于女性（P＜0.001）。2017—2023年低级别上皮内瘤变、高级别上皮内瘤变和早期癌检出率呈波动式下降趋势。各类病变检出率均随着年龄增长呈上升趋势，尤其在>50岁人群中，高级别上皮内瘤变及癌变检出率呈快速上升趋势（P＜0.001）。［结论］ 阆中市食管癌早诊早治项目成效显著，早诊率处于国内较高水平。男性及50岁以上人群是食管癌高危群体，应作为未来筛查与健康教育的重点对象。 |
| 英文摘要: |
| Abstract： ［Objective］ To analyze the results of endoscopic screening for esophageal cancer in the early diagnosis and treatment project in Langzhong City， Sichuan Province from 2017 to 2023. ［Methods］ A cluster sampling method was used to select permanent residents aged 40~69 years in the area for endoscopic screening. Pathological biopsies were performed on suspicious lesions. The detection rates of lesions， early diagnosis rate， and their distribution by gender， age， and year were analyzed. ［Results］ A total of 19 977 people were screened， with a male to female ratio of 1∶1.44 and a mean age of 56.26±7.56 years old. The biopsy rate was 35.18% (7 028/19 977). Low-grade intraepithelial neoplasia was detected in 992 individuals， with a detection rate of 4.97% (992/19 977). Positive cases (high-grade intraepithelial neoplasia， early cancer， and advanced cancer) numbered 349， with a detection rate of 1.75% (349/19 977). Early cases (high-grade intraepithelial neoplasia and early cancer) numbered 316， with a detection rate of 1.58% (316/19 977). The early diagnosis rate was 90.54% (316/349). The detection rates of all lesion grades (low-grade intraepithelial neoplasia， high-grade intraepithelial neoplasia， early cancer， and advanced cancer) were significantly higher in men than that in women (all P<0.001). From 2017 to 2023， the detection rates of low-grade intraepithelial neoplasia， high-grade intraepithelial neoplasia， and early cancer showed a fluctuating downward trend. Detection rates of all lesion types increased with age， with a rapid upward trend in people over 50 years old for high-grade intraepithelial neoplasia and cancer (P<0.001). ［Conclusion］ The early diagnosis and treatment project for esophageal cancer in Langzhong City has achieved remarkable results， with an early diagnosis rate at a relatively high level in China. Men and people over 50 years old are high-risk groups for esophageal cancer and should be prioritized in future screening and health education. |
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