| 朱洪挺,胡 浩,徐玲巧,等.2021年浙江省肿瘤登记地区口腔和咽喉癌发病与死亡现状及2000—2021年趋势分析[J].肿瘤学杂志,2026,32(5):404-410. |
| 2021年浙江省肿瘤登记地区口腔和咽喉癌发病与死亡现状及2000—2021年趋势分析 |
| Incidence and Mortality of Oral and Pharyngeal Cancer in Zhejiang Cancer Registration Areas in 2021 and Trends from 2000 to 2021 |
| 投稿时间：2025-05-23 |
| DOI：10.11735/j.issn.1671-170X.2026.05.B008 |
|
 |
| 中文关键词: 口腔和咽喉肿瘤 发病率 死亡率 变化趋势 浙江 |
| 英文关键词:oral and pharyngeal neoplasms incidence mortality trend Zhejiang |
| 基金项目: |
|
| 摘要点击次数: 10 |
| 全文下载次数: 1 |
| 中文摘要: |
| 摘 要：［目的］ 分析2000—2021年浙江省肿瘤登记地区口腔和咽喉癌的发病、死亡现状及2000—2021年变化趋势。［方法］ 收集2000—2021年浙江省肿瘤登记地区口腔和咽喉癌的发病、死亡数据，计算口腔和咽喉癌的粗发病/死亡率、中国人口标化发病/死亡率（age-standardized incidence rate by Chinese standard population/age-standardized mortality rate by Chinese standard population， ASIRC/ASMRC）、世界人口标化发病/死亡率（age-standardized incidence rate by world standard population/age-standardized mortality rate by world standard population，ASIRW/ASMRW）。采用 Joinpoint Regression Program 4.8.0.1 软件拟合率与年份的对数线性关系，计算平均年度变化百分比（average annual percentage change，AAPC）及95%置信区间，分析趋势变化的统计学意义。［结果］ 2021年浙江省肿瘤登记地区口腔和咽喉癌粗发病率、ASIRC和ASIRW分别为5.54/10万、2.89/10万和2.85/10万，男性ASIRC为女性的2.22倍；口腔和咽喉癌粗死亡率、ASMRC和ASMRW分别为为1.88/10万、0.81/10万和0.82/10万，男性ASMRC为女性的3.32倍，城区男性ASMRC为农村男性的1.18倍。年龄别发病和死亡率在 40 岁（发病率）、50 岁（死亡率）后显著上升，85岁及以上年龄组达峰值。2000—2021年浙江省肿瘤登记地区口腔和咽喉癌总体粗发病率、ASIRC和ASIRW的AAPC分别为4.78%（P＜0.001）、2.62%（P＜0.001）和2.60%（P＜0.001），农村男性增幅最大（粗发病率 AAPC=6.55%）；2000—2021年浙江省肿瘤登记地区口腔和咽喉癌总体粗死亡率、ASMRC和ASMRW的AAPC分别为4.81%（P＜0.001）、1.89%（P=0.008）和2.01%（P=0.030），城市男性增幅最大（粗死亡率 AAPC=8.05%）。［结论］ 2000—2021 年浙江省肿瘤登记地区口腔和咽喉癌发病率和死亡率均呈显著上升趋势，男性（尤其是农村男性发病、城市男性死亡）为高风险人群，需针对性开展健康宣教、早筛早治及三级预防措施，降低疾病负担。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence， mortality status of oral and pharyngeal cancer in cancer regis-tration areas of Zhejiang Province in 2021 and the changing trends from 2000 to 2021.［Methods］ Data on oral and pharyngeal cancer incidence and mortality were collected from the cancer registration regions of Zhejiang Province during 2000—2021. Crude incidence/mortality rates， age-standardized rate by Chinese standard population(ASIRC/ASMRC)， age-standardized rate by world standard population (ASIRW/ASMRW) were calculated. Joinpoint Regression Program 4.8.0.1 was used to fit the Log-linear relationship between rates and years， and the average annual percentage change (AAPC) with 95% confidence interval was calculated to analyze the statistical significance of trend changes. ［Results］ In 2021， the crude incidence rate， ASIRC， and ASIRW of oral and pharyngeal cancer in the cancer registration areas of Zhejiang Province were 5.54/105， 2.89/105， and 2.85/105， respectively， with the ASIRC in male being 2.22 times that in female. The crude mortality rate， ASMRC， and ASMRW of oral and pharyngeal cancer were 1.88/105， 0.81/105， and 0.82/105， respectively； the ASMRC in male was 3.32 times that in female， and the ASMRC of urban males was 1.18 times that of rural males. The age-specific incidence and mortality rates increased significantly after the age of 40 years old (for incidence) and 50 years old (for mortality)， peaking in the age group of 85 years old and above. From 2000 to 2021， the AAPCs of the overall crude incidence rate， ASIRC， and ASIRW of oral and pharyngeal cancer in the cancer registration areas of Zhejiang Province were 4.78% (P＜0.001)， 2.62% (P＜0.001)， and 2.60% (P＜0.001)， respectively， with rural males showing the largest increase (crude incidence rate AAPC=6.55%). During the same period， the AAPCs of the overall crude mortality rate， ASMRC，and ASMRW were 4.81% (P＜0.001)， 1.89% (P=0.008)， and 2.01% (P=0.030)， respectively， with urban males showing the largest increase (crude mortality rate AAPC=8.05%). ［Conclusion］ From 2000 to 2021， the incidence and mortality of oral and pharyngeal cancer in the cancer registration areas of Zhejiang Province both showed a significant upward trend. Males， especially rural males (for incidence) and urban males (for mortality)， are high-risk groups. Targeted interventions such as health education， early screening and treatment， and three-level prevention measures should be implemented to reduce the disease burden. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|