| 褚 洁,沈佳菲,欧 笛,等.超声影像特征指标鉴别淋巴瘤与淋巴结结核的价值：基于171例淋巴结受累患者分析[J].肿瘤学杂志,2025,31(10):890-895. |
| 超声影像特征指标鉴别淋巴瘤与淋巴结结核的价值：基于171例淋巴结受累患者分析 |
| Ultrasound Imaging Characteristics for Differentiating Lymphoma from Lymph Node Tuberculosis： Based on the Analysis of 171 Patients with Lymph Node Involvement |
| 投稿时间：2025-01-24 |
| DOI：10.11735/j.issn.1671-170X.2025.10.B010 |
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| 中文关键词: 淋巴瘤 淋巴结结核 超声检查 影像特征 鉴别诊断 |
| 英文关键词:lymphoma lymph node tuberculosis ultrasonography image feature differential diagnosis |
| 基金项目:杭州市医药卫生科技项目（20220919Y029） |
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| 摘要点击次数: 60 |
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| 中文摘要: |
| 摘 要：［目的］ 探讨超声影像特征指标鉴别诊断淋巴瘤与淋巴结结核的价值。［方法］ 选取2018年1月至2021年12月收治的171例淋巴结受累患者，根据病理结果分为结核组（70例，71枚淋巴结）和淋巴瘤组（101例，101枚淋巴结），比较两组超声影像指标的差异，受试者工作特征（receiver operating characteristic，ROC）曲线分析各指标的鉴别预测价值。［结果］ 淋巴瘤与淋巴结结核组的年龄、性别、淋巴结最大切面纵横比（L/S比值）、淋巴结门是否清晰、有无钙化、有无液化、有无网格或条索样回声、血供分型及血供分级差异均有统计学意义（P<0.05）。多因素Logistic回归分析显示，年龄、L/S比值、淋巴结门是否清晰、有无液化、有无网格或条索样回声、血供分型及血供分级是鉴别淋巴瘤与淋巴结结核的特征指标，上述指标联合鉴别预测的准确率为87.8%，灵敏度为88.5%，特异度为86.8%，ROC曲线下面积为0.962［95%置信区间（confidence interval，CI）：0.94~0.99］，显著高于各指标单独预测（P<0.05）。［结论］ 超声影像特征指标可为鉴别浅表淋巴瘤与淋巴结结核提供一定参考。 |
| 英文摘要: |
| Abstract： ［Objective］ To evaluate the utility of ultrasound imaging characteristics in differentiating lymphoma from lymph node tuberculosis . ［Methods］ A total of 171 patients with lymph node involvement admitted between January 2018 and December 2021 were enrolled. Based on pathological results， patients were divided into a lymph node tuberculosis group (70 cases， 71 lymph nodes) and a lymphoma group (101 cases， 101 lymph nodes). Differences in ultrasound imaging characteristics between the two groups were compared. The differential predictive value of each indicator was assessed using receiver operating characteristic (ROC) curve analysis. ［Results］ Significant differences were observed in age， sex， long-axis to short-axis ratio(L/S ratio)， lymph node hilum clarity， presence of calcification， presence of necrosis (liquefaction)， presence of reticular or cord-like echotexture， color Doppler flow imaging(CDFI) classification， and CDFI grade between the lymphoma and lymph node tuberculosis groups(P<0.05). Multivariate Logistic regression analysis identified age， L/S ratio， lymph node hilum clarity， presence of necrosis， presence of reticular or cord-like echotexture， CDFI classification， and CDFI grade as significant indicators for differentiating lymphoma from lymph node tuberculosis. The combined predictive model incorporating these indicators achieved an accuracy of 87.8%， sensitivity of 88.5%， specificity of 86.8%， and an area under the ROC curve(AUC) of 0.962 (95%CI：0.94~0.99). This combined prediction was significantly superior to any single indicator alone (P<0.05). ［Conclusion］ Ultrasound imaging characteristics can provide valuable reference information for distinguishing superficial lymphoma from lymph node tuberculosis. |
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