| 邓 雷,李芳梅,王煜宁,等.基于临床需求的卵巢癌基因检测规范化选择中国专家共识（2025年版）[J].肿瘤学杂志,2025,31(9):741-752. |
| 基于临床需求的卵巢癌基因检测规范化选择中国专家共识（2025年版） |
| Chinese Expert Consensus on Standardized Selection of Ovarian Cancer Gene Testing Based on Clinical Requirements （Version 2025） |
| 投稿时间：2025-04-15 |
| DOI：10.11735/j.issn.1671-170X.2025.09.B001 |
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| 中文关键词: 卵巢肿瘤 基因检测 专家共识 |
| 英文关键词:ovarian neoplasms gene test expert consensus |
| 基金项目:辽宁省重点研发项目（2024JH2/102500019）；“兴辽英才计划”医学名家项目（XLYC2412037）；沈阳市科技局2023年助力中国医科大学高质量发展专项（23-506-3-01-10）；沈阳市科技计划专项项目（22-321-33-08） |
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| 全文下载次数: 93 |
| 中文摘要: |
| 摘 要：卵巢癌的治疗已由以病理类型、分级、分期为基准的治疗转变为基于卵巢癌生物标志物的精准、个体化、靶向治疗。卵巢癌的基因突变多样，临床工作中针对卵巢癌的基因检测存在检测不足及过度两种情况，目前国内外尚缺乏不同时期治疗节点、基于临床需求的卵巢癌基因检测的规范化方案，本共识制定小组以循证证据为基础，结合国内外文献、相关指南及专家意见，旨在为基于临床需求的卵巢癌基因检测规范化选择提供参考。 |
| 英文摘要: |
| Abstract： The treatment of ovarian cancer has evolved from a traditional approach based on pathological type， grading， and staging to a biomarker-driven paradigm emphasizing precise， personalized， and targeted therapies. Despite substantial genetic heterogeneity in ovarian cancer， current clinical practice reveals both underutilization and inappropriate overuse of genetic testing. Standardized protocols for evidence-based genetic testing tailored to clinical needs at different treatment phases remain undefined in domestic and international guidelines. This consensus， developed by an expert panel through systematic evaluation of evidence， comprehensive review of global literature， and integration of current guidelines and clinical expertise， aims to establish practical recommendations for the rational application of genetic testing in ovarian cancer management across key therapeutic decision points. |
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