| 黄 霜,徐明忠,胡劲松,等.2023—2024年湖南省长沙市结直肠癌筛查成本效果及效益分析[J].肿瘤学杂志,2025,31(8):697-702. |
| 2023—2024年湖南省长沙市结直肠癌筛查成本效果及效益分析 |
| Cost-Effectiveness and Cost-Benefit Analyses of Colorectal Cancer Screening in Changsha City， Hunan Province from 2023 to 2024 |
| 投稿时间：2024-09-26 |
| DOI：10.11735/j.issn.1671-170X.2025.08.B007 |
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| 中文关键词: 结直肠肿瘤 筛查 成本-效果分析 成本-效益分析 湖南 |
| 英文关键词:colorectal neoplasms screening cost-effectiveness analysis cost-benefit analysis Hunan |
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| 中文摘要: |
| 摘 要： ［目的］ 评价2023—2024年湖南省长沙市结直肠癌筛查效果、效益。［方法］ 收集长沙市结直肠癌筛查数据及成本资料，计算问卷高危率、肠镜顺应性、病变检出率，对筛查方案进行成本-效果和成本-效益评价。［结果］ 长沙市结直肠癌筛查共招募61 957人完成问卷调查，高危者17 322人，高危率为27.96%（17 322/61 957）；粪便DNA检测数14 139份，阳性数1 133份，粪便DNA检测阳性率为8.01%（1 133/14 139）；肠镜检测694人，肠镜顺应性为61.25%（694/1 133）。结肠癌、腺瘤及无蒂/广基锯齿状病变等癌前病变、非腺瘤性息肉检出率分别为1.59%（11/694）、42.51%（295/694）和22.48%（156/694）。筛查总成本为367.10万元，总效益为1 285.28万元。成本效益比为1∶3.50。不同病变类型筛查的早期发现成本系数（early detection cost index，EDCI）不同，范围为0.10~2.47，均小于5。［结论］ 2023—2024年长沙市结直肠癌筛查具有良好的经济效果和效益，对长沙市结直肠癌的早期发现、早期诊断、早期治疗起到了推动作用。 |
| 英文摘要: |
| Abstract：［Objective］ To evaluate the cost-effectiveness and cost-benefit of colorectal cancer screening in Changsha City， Hunan Province from 2023 to 2024. ［Methods］ The data of colorectal cancer screening in Changsha City from 2023 to 2024 were collected. The high-risk rate， colonoscopy compliance rate and lesion detection rate were calculated. The cost-effectiveness and cost-benefit evaluation methods of screening programs were evaluated. ［Results］ A total of 61 957 residents attended colorectal cancer screening in Changsha from 2023 to 2024. In risk questionnaire survey， 17 322 (17 322/ 61 957，27.96%) were identified as high-risk subjects， among whom 14 139 subjects underwent gene detection with a positive rate of 8.01% (1 133/14 139)； and 694 subjects underwent colonoscopy with a compliance rate of 61.25% (694/1 133)， and colorectal cancer， precancerous lesions and non-adenomatous polyps were detected in 11 (1.59%)， 295 (42.51%) and 156 cases (22.48%)， respectively. The total cost of screening in this study was 3.671 million Yuan， and the total benefit was 12.852 8 million Yuan. The cost-benefit ratio was 1∶3.50. The early detection cost index (EDCI) of screening for varous lesions was different， ranging from 0.10 to 2.47， all of which were less than 5. ［Conclusion］ The colorectal cancer screening in Changsha City from 2023 to 2024 has played a promoting role in the early detection， diagnosis and treatment of colorectal cancer with a good efficacy and benefit. |
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