| 金海朋,应荣彪,姚 俊,等.2020—2023年浙江省温岭市结直肠癌早诊早治筛查结果分析[J].肿瘤学杂志,2024,30(10):811-816. |
| 2020—2023年浙江省温岭市结直肠癌早诊早治筛查结果分析 |
| Results of Colorectal Cancer Screening in Wenling City of Zhejiang Province from 2020 to 2023 |
| 投稿时间：2024-06-16 |
| DOI：10.11735/j.issn.1671-170X.2024.10.B003 |
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| 中文关键词: 结直肠肿瘤 筛查 早诊早治 浙江 |
| 英文关键词:colorectal neoplasms screening early diagnosis and treatment Zhejiang |
| 基金项目:台州市社会发展类科技项目（22ywb127） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2020—2023年浙江省温岭市结直肠癌早诊早治筛查结果，为优化温岭市结直肠癌筛查策略提供参考依据。［方法］ 2020—2023年，采用整群抽样的方法选取浙江省温岭市50~74周岁的本市户籍居民，采用结直肠癌问卷风险评估和免疫法粪便潜血试验（fecal immunochemical test，FIT）相结合的方法初筛出结直肠癌高危人群，对其行结肠镜检查。［结果］ 浙江省温岭市50~74周岁结直肠癌早诊早治筛查目标人数为380 177人，参与筛查人数为192 205人，参与率为50.56%，高危人数（筛查阳性）为35 428人，高危率为18.43%。共10 213人进行结肠镜检查，依从率为28.83%；共检出病变7 786例，检出率为76.24%，2023年为历年最高达80.44%；其中非腺瘤性良性病变2 160例、非进展期腺瘤3 403例、进展期腺瘤2 048例、结直肠癌175例，检出率分别为21.15%、33.32%、20.05%和1.71%。男性非进展期腺瘤、进展期腺瘤及结直肠癌检出率均高于女性（P均<0.05）。在进展期腺瘤及结直肠癌病例中检出率前3位的城镇分别为石塘镇（32.84%）、石桥头镇（24.31%）、新河镇（23.77%）。［结论］ 浙江省温岭市居民患结直肠癌的风险较高，结肠镜检查依从性良好，非腺瘤性良性病变、非进展期腺瘤、进展期腺瘤的检出率均较高，且呈逐年增加态势，今后结直肠癌筛查工作较为严峻，可适当加强重点区域的防控，探索出适合本区域的筛查模式。 |
| 英文摘要: |
| Abstract：［Objective］ To analyse the results of colorectal cancer early diagnosis and treatment program in Wenling City of Zhejiang Province from 2020 to 2023. ［Methods］ From 2020 to 2023， a cluster sampling method was used to select residents aged 50~74 years in Wenling City. All participants underwent a questionnaire survey on risk assessment of colorectal cancer and fecal immunochemical test (FIT) as initial screening， the high-risk subjects of colorectal cancer were then subject to colonoscopy. ［Results］ Among 380 177 target subjects in Wenling City， 192 205 people participated in screening with a participation rate of 50.56%. A total of 35 428 people were identified as at high risk with a high risk rate of 18.43%， among whom 10 213 people underwent colonoscopy with a compliance rate of 28.83%. Colonoscopy detected 7 786 lesions with a detection rate of 76.24%， 2 160 were non-adenomatous benign lesions， 3 403 were non-progressing adenomas， 2 048 were progressing adenomas， and 175 were colorectal cancers， with a detection rate of 21.15%， 33.32%， 20.05% and 1.71%， respectively. The detection rates of non-progressive adenomas， progressive adenomas and colorectal cancers were higher in males than those in females (all P<0.05). The top three towns with higher detection rates of progressive adenomas and colorectal cancers were Shitang (32.84%)， Shiqiaotou (24.31%) and Xinhe (23.77%). ［Conclusion］ Residents of Wenling City have a high risk of colorectal cancer； the compliance of colonoscopy is generally good； the detection rates of non-adenomatous benign lesions， non-progressing adenomas， and progressing adenomas are high and show a increasing trend from 2020 to 2023. |
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