袁梅琴,朱利明.晚期神经内分泌瘤的药物治疗现状与研究进展[J].肿瘤学杂志,2024,30(5):371-378. |
晚期神经内分泌瘤的药物治疗现状与研究进展 |
Current Status and Progress on Drug Therapy for Advanced Neuro-endocrine Tumor |
投稿时间:2024-01-19 |
DOI:10.11735/j.issn.1671-170X.2024.05.B004 |
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中文关键词: 神经内分泌肿瘤 神经内分泌瘤 生长抑素类似物 靶向治疗 免疫治疗 |
英文关键词:neuroendocrine neoplasm neuroendocrine tumor somatostatin analogues targeted therapy immunotherapy |
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中文摘要: |
摘 要:神经内分泌肿瘤起源于肽能神经元和神经内分泌细胞,临床上可表现从惰性、低度恶性到显著恶性的一系列高度异质的生物学行为。神经内分泌瘤属于分化良好的肿瘤,恶性程度低于神经内分泌癌。晚期神经内分泌瘤多以药物治疗为主。全文就晚期神经内分泌瘤的药物治疗现状及研究进展进行综述。 |
英文摘要: |
Abstract: Neuroendocrine neoplasm (NEN) is malignant tumor originated from peptideric neurons and neuroendocrine cells. NEN has significant heterogeneity and clinically manifests a series of biological behaviors from inert, low malignant to prominent malignant. Compared to neuroendocrine carcinoma, neuroendocrine tumor (NET) is a well-differentiated and lower malignancy type of NEN, and drug therapy is the main treatment for advanced NET. This paper reviews the current status and progress on drug therapy for advanced NET. |
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