| 石柴琴,罗利琼.放疗在肝细胞癌合并门脉癌栓治疗中的应用研究进展[J].肿瘤学杂志,2024,30(4):328-334. |
| 放疗在肝细胞癌合并门脉癌栓治疗中的应用研究进展 |
| Progress on Radiotherapy in Treatment of Hepatocellular Carcinoma Complicated with Portal Vein Cancer Thrombus |
| 投稿时间：2023-05-23 |
| DOI：10.11735/j.issn.1671-170X.2024.04.B010 |
|
 |
| 中文关键词: 肝细胞癌 门静脉癌栓 放射疗法 免疫检查点抑制剂 |
| 英文关键词:hepatocellular carcinoma portal vein cancer thrombus radiation therapy immune checkpoint inhibitors |
| 基金项目:国家自然科学基金（81773264） |
|
| 摘要点击次数: 219 |
| 全文下载次数: 134 |
| 中文摘要: |
| 摘 要：肝细胞癌（hepatocellular carcinoma，HCC）因其高患病率和死亡率成为癌症研究的热点。HCC合并门静脉癌栓（portal vein tumor thrombosis，PVTT）的存在及其位置是HCC临床分期、治疗效果、预后的关键因素。对于HCC合并PVTT的治疗，目前还没有全球性的共识或指南，其治疗仍是一个巨大的挑战。放疗作为多种实体瘤的重要治疗手段，可靶向治疗侵犯血管，随着精准放疗时代的到来，单独使用放疗或联合其他治疗可改善PVTT患者的生存期和生活质量。近年来放疗在PVTT患者可手术治疗的围手术期、不可手术姑息治疗方面的研究层出不穷，全文就近年来相关研究进展作一综述。 |
| 英文摘要: |
| Abstract： Hepatocellular carcinoma(HCC) has always been a hot spot in cancer research due to its high morbidity and mortality. The presence and location of portal vein tumor thrombosis(PVTT) is a key factor for the clinical staging， treatment outcome and prognosis of HCC patients. Currently， the treatment of HCC combined with PVTT remains a great challenge， and there is no global consensus or guidelines for its treatment. The modern radiotherapy can target the invading blood vessels precisely， the use of radiotherapy alone or in combination with other therapeutic modalities can improve the survival and quality of life of patients with PVTT. This paper reviews the recent progress on the application of radiotherapy in the perioperative treatment or palliative treatment for inoperable patients with PVTT. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |