刘 姗,徐海燕,于 雷,等.简明急性生理功能评分Ⅱ在恶性肿瘤急诊危重患者近期死亡中的预测价值分析[J].肿瘤学杂志,2023,29(11):948-952.
简明急性生理功能评分Ⅱ在恶性肿瘤急诊危重患者近期死亡中的预测价值分析
The Value of Simplified Acute Physiology Score Ⅱ in Predicting Recent Mortality of Patients with Malignant Tumor in Emergency Department
投稿时间:2023-04-03  
DOI:10.11735/j.issn.1671-170X.2023.11.B009
中文关键词:  简明急性生理功能评分Ⅱ  恶性肿瘤  急诊  预后
英文关键词:simplified acute physiology score Ⅱ  malignant tumor  emergency  prognosis
基金项目:中国癌症基金会北京希望马拉松专项基金
作者单位
刘 姗 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院 
徐海燕 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院 
于 雷 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院 
丛明华 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院 
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中文摘要:
      摘 要:[目的] 探讨简明急性生理功能评分Ⅱ(SAPS Ⅱ)对恶性肿瘤急诊危重患者近期死亡风险的预测价值。[方法] 采用单中心随机选取2019年12月1日至2021年11月1日在中国医学科学院肿瘤医院综合科急诊室就诊的恶性肿瘤危重患者101例(生命体征不平稳或意识障碍等),按照14 d是否死亡分为死亡组和存活组。绘制SAPS Ⅱ评分对于所有患者近期死亡预测受试者工作特征曲线(ROC曲线),并对SAPS Ⅱ评分各变量对预后的影响进行线性回归分析。[结果] 101例患者中,死亡组25例,存活组76例。死亡组的SAPS Ⅱ分值显著高于存活组(50.20±16.02 vs 36.22±10.00,P<0.001)。SAPS Ⅱ评分对预后预测的ROC曲线下面积为0.757,截断值为53.0。Glasgow评分、尿量、收缩压是患者在14 d内死亡的高危因素。[结论] SAPS Ⅱ评分能够较好地判断急诊恶性肿瘤危重患者近期预后,在预检分诊中具有重要作用。
英文摘要:
      Abstract:[Objective] To evaluate the value of simplified acute physiology score Ⅱ (SAPS Ⅱ) in predicting recent mortality risk of patients with malignant tumor in emergency department. [Methods] A prospective research method was conducted. Clinical data of 101 emergency patients (with unstable vital signs or disturbance of consciousness) admitted to General Department of National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College from December 1st, 2019 to November 1st, 2021 were collected. According to their outcomes, the 101 patients were divided into 2 groups, which were the death group (dead within 14 d) and the survival group (not dead within 14 d). Receiver operating characteristic curve (ROC) of SAPS Ⅱ was created to assess the value of predicting recent mortality of patients with malignant tumors in emergency department. Linear regression analysis of SAPS Ⅱ scoring variables was practised. [Results] Among 101 patients, there were 25 in the death group and 76 in the survival group. The SAPS Ⅱ in the death group was significantly higher than that in the survival group(50.20±16.02 vs 36.22±10.00, P<0.001). AUC of SAPS Ⅱ for prognosis prediction was 0.757, and the cut-off value was 53.0. Glasgow score, urine output and systolic pressure were high risk factors for death within 14 d. [Conclusion] SAPS Ⅱ can be used to predict recent mortality risk of patients with malignant tumors in emergency department and has a clinical signi-ficance in pre-examination .
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