| 秦方圆,王静萱.三阳性乳腺癌转移的分子机制研究进展[J].肿瘤学杂志,2023,29(7):606-610. |
| 三阳性乳腺癌转移的分子机制研究进展 |
| Progress on Molecular Mechanisms of Metastasis of Triple Positive Breast Cancer |
| 投稿时间：2022-11-21 |
| DOI：10.11735/j.issn.1671-170X.2023.07.B009 |
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| 中文关键词: 三阳性乳腺癌 激素受体 肿瘤转移 上皮间质转化 |
| 英文关键词:triple-positive breast cancer hormone receptor tumor metastasis epithelial-mesenchymal transformation |
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| 摘要点击次数: 462 |
| 全文下载次数: 186 |
| 中文摘要: |
| 摘 要：三阳性乳腺癌作为一种特殊类型的乳腺癌亚型，其转移性更强且具有更高的侵袭性。大量研究表明，三阳性乳腺通过激素受体的异常表达、上皮细胞间质转化等多种分子机制实现其远端转移和侵袭。全文就三阳性乳腺癌的临床特征及其转移的分子机制进行综述，期望为三阳性乳腺癌的临床治疗提供新的思路。 |
| 英文摘要: |
| Abstract： Triple-positive breast cancer, as a special type of breast cancer, is highly metastatic and aggressive. Studies have shown that the abnormal expression of hormone receptors and epithelial-mesenchymal transformation of mammary gland may be the molecular mechanism of distal metastasis and invasion in triple-positive breast cancer. This paper reviews the clinical characteristics and molecular mechanism of metastasis in triple-positive breast cancer, to provide new insights for clini-cal treatment of triple-positive breast cancer in the future. |
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