| 高 欣,仇公才,于少博,等.ABHD11-AS1在肿瘤中表达及调控作用研究[J].肿瘤学杂志,2022,28(6):504-509. |
| ABHD11-AS1在肿瘤中表达及调控作用研究 |
| Research Progress on Expression and Regulatory Mechanism of ABHD11-AS1 in Tumors |
| 投稿时间：2022-02-02 |
| DOI：10.11735/j.issn.1671-170X.2022.06.B011 |
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| 中文关键词: 长链非编码RNA ABHD11-AS1 肿瘤 表达 调控作用 |
| 英文关键词:long non-coding RNA ABHD11-AS1 tumor expression regulatory mechanism |
| 基金项目:黑龙江省自然科学基金（LH2020H058）；湖北陈孝平科技发展基金（CXPJJH12000002-2020015） |
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| 中文摘要: |
| 摘 要：长链非编码RNA（long non-coding RNA，lncRNA）是一类长度>200 nt且不具备编码蛋白质能力的非编码RNA。大量研究表明lncRNA在恶性肿瘤发生发展中起着重要作用。ABHD11-AS1作为一种lncRNA在诸多人类肿瘤中呈现异常表达，并能够调控肿瘤增殖和侵袭、迁移等恶性生物学行为。全文对ABHD11-AS1在肿瘤中的表达及调控作用进行综述。 |
| 英文摘要: |
| Abstract： Long non-coding RNA(lncRNA) is a type of RNA that does not encode proteins with a length of more than 200 nucleotides. Plenty of studies suggest that lncRNA plays important roles in the occurrence and development of malignant tumors. ABHD11-AS1 as lncRNA， is aberrantly expressed in various human cancers and can regulate the malignant biological behaviors including proliferation， invasion and metastasis. This article reviews the expression and regulatory mechanism of ABHD11-AS1 in neoplasms. |
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