| 章浙伟,郑家平,邵国良.肝动脉灌注化疗治疗肝脏恶性肿瘤的研究进展[J].肿瘤学杂志,2022,28(4):315-321. |
| 肝动脉灌注化疗治疗肝脏恶性肿瘤的研究进展 |
| Research Progress of Hepatic Arterial Infusion Chemotherapy in Treatment of Hepatic Malignant Tumors |
| 投稿时间：2021-08-15 |
| DOI：10.11735/j.issn.1671-170X.2022.04.B011 |
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| 中文关键词: 肝动脉灌注化疗 肝动脉化疗栓塞术 肝细胞癌 索拉非尼 |
| 英文关键词:hepatic artery infusion chemotherapy transcatheter arterial chemoembolization hepatocellular carcinoma sorafenib |
| 基金项目:国家自然科学基金（82072032）；湖北陈孝平科技发展基金会2020年度肝癌诊疗交流基金（CXPJJH1200008-13） |
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| 中文摘要: |
| 摘 要：肝动脉灌注化疗（hepatic artery infusion chemotherapy，HAIC）是常用的介入治疗方法，通过将抗肿瘤药物直接灌注至肝脏肿瘤的供血动脉内起效，目前已成为晚期肝细胞癌（hepatocellular carcinoma，HCC）治疗的重要手段之一。同时HAIC治疗也用于转移性及其他非HCC肝脏恶性肿瘤，可作为一种安全有效的补充治疗方法。近年来，HAIC越来越受到国内外学者的关注，其临床推广应用不断被探索。全文从HAIC的发展历史、应用原理机制、用药方案、临床应用研究、未来研究方向等方面作一综述。 |
| 英文摘要: |
| Abstract： Hepatic artery infusion chemotherapy(HAIC) is a common interventional therapy. It takes effect by directly injecting antineoplastic drugs into the blood supply vessels of hepatic tumors. At present， it has become one most important methods in the treatment of advanced hepatocellular carcinoma(HCC). At the same time， HAIC can also work on metastatic tumors and other non-HCC hepatic malignant tumors as a safe and effective complementary therapy. In recent years， HAIC has drawn more and more attention from clinicians and its clinical application has been explored continuously. This article reviews the history， application principle， dosage regimen， clinical application and future research direction of HAIC. |
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