黄 珍,谢玉洁,李黎荟.乳腺癌伴1~2枚前哨淋巴结转移腋窝外科处理的研究进展[J].肿瘤学杂志,2021,27(12):991-996.
乳腺癌伴1~2枚前哨淋巴结转移腋窝外科处理的研究进展
Advances in Axillary Surgical Management of Breast Cancer with One or Two Sentinel Lymph Node Metastases
中文关键词  
DOI:10.11735/j.issn.1671-170X.2021.12.B004
中文关键词:  乳腺肿瘤  前哨淋巴结活检  腋窝淋巴结清扫
英文关键词:breast cancer  sentinel lymph node biopsy  axillary lymph node dissection
基金项目:广西壮族自治区卫生健康委自筹经费科研课题(z20200134)
作者单位
黄 珍 广西壮族自治区人民医院广西医学科学院 
谢玉洁 广西医科大学研究生学院 
李黎荟 广西医科大学研究生学院 
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中文摘要:
      摘 要:乳腺癌腋窝手术对确立临床分期、辅助治疗选择及预后判断均有重要价值。临床淋巴结阴性的乳腺癌,应用前哨淋巴结活检(SLNB)确定腋窝淋巴结分期已成为标准。对于前哨淋巴结(SLN)阴性的乳腺癌,腋窝淋巴结清扫(ALND)可以避免;而对于SLN阳性的乳腺癌,ALND仍是标准的腋窝处理方式。然而,在SLN阳性患者中进一步行ALND后发现,在仅1~2枚SLN阳性患者中,61.4%~64.5%非前哨淋巴结(nSLN)为阴性。已有大量的临床研究探索了特定条件下的1~2枚SLN阳性患者免除ALND的可行性与安全性。全文就乳腺癌伴1~2枚SLN转移腋窝外科处理的相关研究进行综述。
英文摘要:
      Abstract: Axillary surgery for breast cancer is of great value in determining clinical stage, adjuvant treatment and prognosis. In clinically lymph node-negative breast cancer, the use of sentinel lymph node biopsy(SLNB) to determine axillary lymph node staging has become the standard protocol. For sentinel lymph node(SLN) negative breast cancer, axillary lymph node dissection(ALND) can be avoided; while for SLN positive breast cancer, ALND is still the standard axillary treatment. However, it has been revealed that in patients with only one or two positive SLN, 61.4% to 64.5% non-sentinel lymph nodes(nSLN) were negative as shown by further ALND. A large number of clinical studies have explored the feasibility and safety of ALND exemption in one or two SLN positive patients under certain conditions. This article reviews the recent progress on the surgical management of breast cancer with one or two SLN metastases.
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