| 陈泓羽,雷小林,杨 蕾.先进外照射光子剂量算法与笔形束卷积算法在鼻咽癌旋转容积调强放疗剂量学分布中的应用[J].肿瘤学杂志,2021,27(11):922-925. |
| 先进外照射光子剂量算法与笔形束卷积算法在鼻咽癌旋转容积调强放疗剂量学分布中的应用 |
| Comparison of Acuros XB Algorithm and PBC Algorithm in Dosimetric Distribution of RapidArc Radiotherapy for Patients with Nasopharyngeal Carcinoma |
| 投稿时间：2021-06-02 |
| DOI：10.11735/j.issn.1671-170X.2021.11.B005 |
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| 中文关键词: 先进外照射光子剂量算法 笔形束卷积算法 鼻咽癌 旋转容积调强放疗 剂量学分布 |
| 英文关键词:advanced external photon dose algorithm pen beam convolution algorithm nasopharyngeal carcinoma rotation volume intensity modulation radiotherapy dose distribution |
| 基金项目:四川省国际科技创新合作/港澳台科技创新合作项目（2020YFH0194） |
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| 中文摘要: |
| 摘 要：［目的］ 对比分析先进外照射光子剂量算法（advanced external photon dose algorithm，Acuros XB算法）与笔形束卷积算法（pen-shaped beam convolution algorithm，PBC算法）在鼻咽癌患者旋转容积调强放疗（rotational volume adjustment of intensive radiotherapy，RapidArc）剂量学分布中的应用价值。［方法］ 选取2020年6月至2020年12月于攀枝花市中西医结合医院肿瘤科行RapidArc放疗治疗的40例鼻咽癌患者作为研究对象，对比分析Acuros XB算法和PBC算法在鼻咽癌患者RapidArc放疗中的剂量学分布。［结果］ 两种算法在靶区Dmean、D5、D95上对比差异无统计学意义（P均>0.05）。与PBC算法相比，Acuros XB算法在靶区适合度指数上对比更高，均匀性指数上对比更低（（P均<0.05）。与PBC算法相比，Acuros XB算法在视神经、晶体、脑干、脊髓等危及器官的最大剂量值更低（P均<0.05）。Delta4验证结果显示，PBC算法和Acuros XB算法的γ通过率均高于90%，两组算法对比差异无统计学意义。两种算法点剂量误差均符合临床要求。［结论］ 与PBC算法相比，Acuros XB算法在鼻咽癌RapidArc放疗中所获得的靶区和危及器官剂量学参数总体上较优。 |
| 英文摘要: |
| Abstract：［Objective］ To compare the application of advanced external photon dose algorithm(acuros XB algorithm) and pen-shaped beam convolution algorithm(PBC algorithm) in dosimetric distribution of rotational volume intensive radiation therapy(RapidArc) for nasopharyngeal carcinoma patients. ［Methods］ The application value of Acuros XB algorithm and PBC algorithm in the metrological distribution of RapidArc radiotherapy for nasopharyngeal carcinoma patients was analyzed and compared. ［Results］ The difference between the two algorithms was not statistically significantin target area Dmean， D5 and D95(all P>0.05). Compared with PBC algorithm， the acuros XB algorithm was higher in target fit index and lower in evenness index(P all<0.05). Compared with PBC algorithm， acuros XB algorithm had lower maximum dose value in optic nerve， lens， brain stem， spinal cord and other organs at risk(all P<0.05). Delta4 validation results showed that the gamma pass rate of PBC algorithm and acuros XB algorithm were higher than 90%， and there was no significant difference between the two groups. The point dose error of both algorithms met the clinical requirements. ［Conclusion］ The target area and organ-threatening dosimetric parameters obtained by Acuros XB algorithm are better than those by PBC algorithm in RapidArc radiotherapy for nasopharyngeal carcinoma patients. |
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