| 张 李,王昕宇,王鹏亮.腹腔镜对比开腹手术治疗胃部胃肠间质瘤的疗效研究[J].肿瘤学杂志,2021,27(6):450-454. |
| 腹腔镜对比开腹手术治疗胃部胃肠间质瘤的疗效研究 |
| Comparison of Laparoscopic and Open Resection for Gastric Gastrointestinal Stromal Tumor |
| 投稿时间：2021-02-18 |
| DOI：10.11735/j.issn.1671-170X.2021.06.B007 |
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| 中文关键词: 胃肠间质瘤 手术 腹腔镜 疗效 |
| 英文关键词:gastrointestinal stromal tumor surgery laparoscopic effect |
| 基金项目:国家自然科学基金（ 81572372，81974373）；国家重点研发计划重大慢性非传染行疾病防控研究(2016YFC1303202)；国家重点研发计划精准医学研究（2017YFC0908304） |
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| 中文摘要: |
| 摘 要：［目的］ 探讨腹腔镜对比开腹手术治疗胃胃肠间质瘤（GIST）的适应证、安全性及短期临床疗效。［方法］ 回顾性分析118例接受腹腔镜及开腹手术治疗的原发胃GIST患者的临床病理资料、手术相关数据和短期临床疗效。［结果］开腹组和腹腔镜组的手术时间分别为（96.8±34.6）min和（96.3±36.5）min，差异无统计学意义。腹腔镜组在术中出血、术后自主排气时间、术后疼痛评分、术后住院时间上均优于开腹组，差异有统计学意义（P<0.05）。全组患者均获随访，无死亡病例。两组在术后复发或转移、术后并发症方面差异无统计学意义。［结论］腹腔镜手术治疗胃GIST安全有效，患者术中出血少，术后恢复快。 |
| 英文摘要: |
| Abstract：［Objective］ To compare efficacy of laparoscopic and open surgery for gastric gastrointestinal stromal tumor(GIST). ［Methods］ The clinicopathologic data，operative parameters and short-term clinical efficacy of 118 patients with primary gastric GIST，who underwent tumor resection in Tianjin Medical University Cancer Hospital from January 2014 to September 2017，were retrospectively analyzed，including 65 cases received open surgery and 53 cases received laparoscopic surgery. ［Results］ The operation time of the open group and the laparoscopic group were(96.8±34.6) min and(96.3±36.5) min，respectively(P>0.05). The laparoscopic group was better than the open group in intraoperative bleeding，postoperative autonomous exhaust time，postoperative pain score，and postoperative hospital stay(P<0.05). All patients were followed up，and no fatal cases were found. There was no significant difference in recurrence or metastasis and postoperative complications between the two groups.［Conclusion］ Laparoscopic surgery is safe and effective in the treatment of gastric GIST with advantages of less intraoperative bleeding and rapid postoperative recovery. |
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