| 田 明,吴玉梅.ROMA模型在卵巢上皮性癌诊断中的应用价值[J].肿瘤学杂志,2021,27(1):9-14. |
| ROMA模型在卵巢上皮性癌诊断中的应用价值 |
| Value of ROMA Model in Diagnosis of Epithelial Ovarian Cancer |
| 投稿时间：2020-02-23 |
| DOI：10.11735/j.issn.1671-170X.2021.01.B003 |
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| 中文关键词: 卵巢恶性肿瘤风险模型 恶性风险指数 哥本哈根指数 卵巢上皮性癌 诊断 |
| 英文关键词:risk ovarian malignancy algorithm risk of malignancy index Copenhagen index epithelial ovarian cancer diagnosis |
| 基金项目: |
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| 中文摘要: |
| 摘 要：卵巢上皮性癌发病隐匿，早期诊断困难，死亡率居女性生殖系统恶性肿瘤第一位，但缺乏临床上理想的肿瘤标志物。因此，探索新的、有效的早期诊断卵巢上皮性癌的方法至关重要。近期，有研究表明卵巢恶性肿瘤风险模型（risk ovarian malignancy algorithm，ROMA）数学模型对预测早期卵巢上皮性癌的诊断具有较高的价值。全文将ROMA 与癌抗原125（cancer antigen 125，CA125）、人附睾蛋白4（human epididymis protein 4，HE4）、恶性风险指数、哥本哈根指数等临床常用的检测指标及数学计算模型对卵巢上皮性癌的诊断效能进行比较，阐述其在临床应用中的进展。 |
| 英文摘要: |
| Abstract：Ovarian cancer is a common gynecologic malignancy. The epithelial ovarian cancer is usually insidious in onset and is difficult to be diagnosed at the early stage，and its mortality rate ranks first among malignant tumors of the female reproductive system. There is lack of ideal clinical tumor markers，therefore，it is of great significance to explore effective early diagnostic methods for epithelial ovarian cancer. Recent studies have shown that the mathematical model risk ovarian malignancy algorithm(ROMA) had high value in the diagnosis of epithelial ovarian malignancy at early stages. In this article，the diagnostic efficacy of ROMA，and CA125，HE4，risk of malignancy index，Copenhagen index，and other commonly used clinical markers and mathematical models are compared in the diagnosis of epithelial ovarian cancer，and the article also elaborates the progress of ROMA model and its clinical application. |
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