| 应 微,李晓阳,刘力豪.分次内锥形束CT扫描联合Fraxion放疗体位固定系统在颅内肿瘤立体定向放疗中的应用[J].肿瘤学杂志,2020,26(5):424-427. |
| 分次内锥形束CT扫描联合Fraxion放疗体位固定系统在颅内肿瘤立体定向放疗中的应用 |
| Application of Intra-fraction Cone Beam CT Combined with Fraxion Localization System of Radiotherapy in Stereotactic Radiotherapy of Intracranial Tumors |
| 投稿时间：2020-01-03 |
| DOI：10.11735/j.issn.1671-170X.2020.05.B011 |
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| 中文关键词: 分次内锥形束CT扫描 Fraxion放疗体位固定系统 六维移动治疗床 摆位误差 |
| 英文关键词:intra-fraction cone beam CT fraxion localization system of radiotherapy six-degree bed setup error |
| 基金项目:四川省科技计划项目（2019JDKP0057） |
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| 中文摘要: |
| 摘 要：［目的］ 探讨分次内CT扫描联合Fraxion体位固定系统在颅内肿瘤立体定向放疗(SRT)中的应用。［方法］ 随机选取25例行SRT的颅内肿瘤放疗患者，应用Fraxion框架固定后行CT扫描，扫描图像与计划参考图像配准，得到左右（LR）、头脚（SI）、前后方向（AP）的平移误差和绕左右（Roll LR）、绕头脚（Roll SI）、绕前后方向（Roll AP）的旋转误差。用六维治疗床校正摆位误差，行SRT治疗同时行分次内CT扫描。再次配准，并记录结果逐弧配准，重复此步骤直到治疗结束。［结果］该组患者首次配准LR、SI、AP方向的平移误差和Roll LR、Roll SI、Roll AP的旋转误差分别为(0.35±0.12)cm、(0．39±0.10)cm、(0．33±0.10)cm和(1.56±0.26)°、(0.53±0.29)°、（0．48±0.28）°，平移误差均在4mm以内，旋转误差<2°，分次内CT扫描误差分别为(0．19±0．05)cm、(0.18±0．07)cm、(0.14±0.06)cm、和(O.32±0.13)°、(O.31±0.10)°、（0.31±0.14）°，平移误差减小，控制在0.2cm以内，旋转误差在0.4°以内，两两比较差异有统计学意义(P均<0.05)。［结论］ 分次内CT扫描联合Fraxion框架在颅内肿瘤SRT中是行之有效的，在治疗时间稍长的情况下保证治疗精度。建议在行SRT时，采用分次内CT扫描逐弧体位验证以减少治疗中的误差。 |
| 英文摘要: |
| Abstract：［Objective］ To evaluate the application of intra-fraction cone beam CT(CBCT) combined with fraxion localization system in stereotactic radiotherapy(SRT） of intracranial tumors. ［Methods］ Twenty-five patients with intracranial tumor undergoing SRT were enrolled in the study. Fraxion localization system fixtures and CBCT scan were performed before each stereotactic radiotherapy，the scanned pictures were matched with the plan reference images. The setup errors on left-right(LR)，superior-inferior(SI) and anterior-post(AP) directions，rotation errors on roll left-right（Roll LR），roll superior-inferior（Roll SI）and roll superior-inferior(Roll AP）were obtained. Six-degree bed was used to correct the setup error. Then SRT was performed and split intra-fraction cone beam CT(CBCT) was performed at the same time. The setup errors and rotation errors were obtained again then six-degree bed was used to correct the errors. This step was repeated until the treatment is finished. ［Results］ The first errors of 25 patients were(0.35±0.12)cm，(0.39±0.10)cm，(0.33±0.10)cm and(1.56±0.26)°，(0.53±0.29)°，（0.48±0.28）° on LR，SI and AP directions rotation errors on Roll LR，Roll SI，and Roll AP，respectively. The translation error was within 4mm and the rotation error is less than 2°. The errors of intra-fraction cone beam CT(CBCT) were(0.19±0.05)cm，(0.18±0.07)cm，(0.14±0.06)cm and(0.32±0.13)°，(0.31±0.10)°，（0.31±0.14）° on LR，SI and AP directions，rotation errors on Roll LR，Roll SI，and Roll AP，respectively. The translation errors were reduced to within 0.2cm，while the rotation errors were also controlled to within 0.4°. The difference between the two was statistically significant(all P<0.05). ［Conclusion］ Application of intra-fraction cone beam CT combined with fraxion localization system in SRT of intracranial tumors is feasible. The accuracy of treatment can be ensured under the condition that the treatment time is slightly longer. During SRT of intracranial tumors，it is necessary to perform arc by arc setup error verification． |
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