| 张思燚,谢长生.免疫检查点抑制剂相关肺炎的研究进展及管理策略[J].肿瘤学杂志,2020,26(5):391-395. |
| 免疫检查点抑制剂相关肺炎的研究进展及管理策略 |
| Research Progress and Management Strategy of Checkpoint Inhibitors Pneumonitis |
| 投稿时间：2019-12-21 |
| DOI：10.11735/j.issn.1671-170X.2020.05.B005 |
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| 中文关键词: 免疫检查点抑制剂 免疫检查点抑制剂相关肺炎 管理策略 |
| 英文关键词:immune checkpoint inhibitors checkpoint inhibitors pneumonitis management strategy |
| 基金项目:国家自然科学基金（81774233） |
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| 摘要点击次数: 1427 |
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| 中文摘要: |
| 摘 要：免疫检查点抑制剂的应用为临床治疗恶性肿瘤带来突破性进展的同时，其伴随的免疫相关不良反应对治疗及预后产生不良影响，其中免疫检查点抑制剂相关肺炎发生率较高，且对患者生存产生了不良影响。关于免疫检查点抑制剂相关肺炎的发生机制、诊断、治疗和预后都还处于探索阶段，尚无定论。全文就免疫检查点抑制剂相关肺炎的研究进行综述，以在临床上更好地监测和管理免疫检查点抑制剂相关肺炎患者。 |
| 英文摘要: |
| Abstract：While the application of immunocheckpoint inhibitors has made a breakthrough in the clinical treatment of malignant tumors，its associated immune-related adverse reactions have a negative impact on the treatment and prognosis，among which，the incidence of checkpoint inhibitors pneumonitis is relatively high and has a negative impact on the survival of patients. However，the monitor，diagnosis and therapeutic methods are not sure yet，remaining further study. The research study on checkpoint inhibitors pneumonitis are reviewed in this paper in order to better monitor and manage patients with checkpoint inhibitors pneumonitis. |
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