潘雅斯,赵 晨,舒宇航.背根神经节在骨癌痛中的研究进展[J].肿瘤学杂志,2020,26(4):350-353. |
背根神经节在骨癌痛中的研究进展 |
Research Progress of Dorsal Root Ganglion in Cancer-induced Bone Pain |
投稿时间:2019-04-01 |
DOI:10.11735/j.issn.1671-170X.2020.04.B015 |
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中文关键词: 背根神经节 骨癌痛 机制 治疗 |
英文关键词:dorsal root ganglion bone cancer pain mechanism treatment |
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中文摘要: |
摘 要:癌症引起的疼痛是严重的慢性疼痛之一,而骨转移性癌痛困扰着大部分晚期癌症患者。脊髓背根神经节(dorsal root ganglion,DRG)无论在解剖学结构还是功能学位置均位于外周和中枢神经系统的交界处,具有传导和调节内脏感觉的作用,在骨转移性癌痛的发生及发展中扮演重要角色。全文综述了关于DRG在骨癌痛研究的最新文献,以期阐明两者的关系有助于寻找治疗或缓解癌症疼痛的有效措施。 |
英文摘要: |
Abstract:Many patients with advanced cancer suffer from metastatic bone cancer pain,and the cancer-induced pain is one of the most serious chronic pains. Dorsal root ganglion(DRG) is located at the junction of peripheral and central nervous system anatomically and functionally,and has the function of transmitting and regulating visceral sensation in the occurrence and development of metastatic bone cancer pain. This article reviews the recent research progress on the roles of DRG in cancer-induced bone pain,aiming to find effective measures to treat or alleviate cancer-induced bone pain. |
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