中文关键词: LncRNA 宫颈癌 临床诊断 生物标志物 |
英文关键词:long non-coding RNA cervical cancer clinical diagnosis biomarker |
基金项目:国家自然科学基金面上项目(81772274) |
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中文摘要: |
摘 要:长链非编码RNA(long non?鄄coding RNA,lncRNA)是长度>200个核苷酸(nt)且无蛋白质编码功能的RNA。近几年研究报道,长链非编码RNA似乎是各种过程中的关键调节剂,并且对肿瘤的发生有严重影响。全文探讨lncRNAs、MALAT1、HOTAIR、CCHE1、BLACAT1、EBIC、ANRIL、SNHG16、NEAT1和SNHG20在宫颈癌发生发展中的作用。 |
英文摘要: |
Abstract:Long non-coding RNAs(lncRNAs) are a group of RNA longer than 200 nucleotides without protein coding function. In recent years,studies have indicated that lncRNAs are a key regulator in various biological process and has a considerable impact on the occurrence of tumors. This article reviews the research progress on the roles of lncRNAs MALAT1,HOTAIR,CCHE1,BLACAT1,EBIC,ANRIL,SNHG16,NEAT1,and SNHG20 in the occurrence and development of cervical cancer. |
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