| 晏 燕,孔为民,王焜煜.首都医科大学附属北京妇产医院1998~2017年卵巢癌病例特点分析[J].肿瘤学杂志,2019,25(7):593-596. |
| 首都医科大学附属北京妇产医院1998~2017年卵巢癌病例特点分析 |
| Analysis of Ovarian Cancer Cases in Beijing Obstetrics and Gynecology Hospital，Capital Medical University from 1998 to 2017 |
| 投稿时间：2018-04-24 |
| DOI：10.11735/j.issn.1671-170X.2019.07.B001 |
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| 中文关键词: 卵巢癌 年龄 病理组织学 临床分期 |
| 英文关键词:ovarian cancer age histopathology clinical stage |
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| 中文摘要: |
| 摘 要：［目的］ 探讨首都医科大学附属北京妇产医院近20年间收治卵巢癌病例特点的变化。［方法］ 收集1998年1月至2017年12月首都医科大学附属北京妇产医院收治的北京籍卵巢癌患者1075例为研究对象。采用回顾性分析法，从发病年份、年龄、组织病理学类型、手术-病理分期等分析20年间卵巢癌病例特点的变化。［结果］ ＜40岁组患者构成比从1988~2007年的28.03%下降到2008~2017年的14.17%（P＜0.05），40～60岁组及＞60岁组卵巢癌构成比分别由1998~2007年的57.50%及14.47%上升到2008~2017年的66.48%及19.34%（P＜0.05）。不同年份组主要病理类型是上皮性卵巢癌，且构成比从1998~2007年的72.56%上升至2008~2017年的90.80%（P＜0.05）。生殖细胞肿瘤及性索-间质肿瘤构成比均有下降，分别由1998~2007年的13.56%及12.66%下降到2008~2017年的3.83%及4.79%（P＜0.05）。上皮性卵巢癌在40岁及以上年龄组是主要病理类型，特别是＞60岁老年患者。年轻患者病理类型构成中，上皮性卵巢癌从1998~2007年的38.71％上升至2008~2017年的68.92%（P＜0.05），生殖细胞肿瘤从1998~2007年的45.80％下降至2008~2017年的20.27%（P＜0.05）。年轻患者多为Ⅰ期，Ⅲ期及以上卵巢癌患者所占比例从1998~2007年的46.11%上升到2008~2017年的60.34%（P＜0.05）。［结论］ 20年来卵巢癌主要发病人群年龄仍以40～60岁为主。上皮性卵巢癌是主要的病理类型，特别是＞60岁老年患者人群，在年轻患者中其构成比呈上升趋势。 |
| 英文摘要: |
| Abstract：［Objective］ To analyze the characteristics of ovarian cancer cases in Beijing Obstetrics and Gynecology Hospital，Capital Medical University from 1998 to 2017.［Methods］ The clinical and pathological data of 1075 patients with ovarian cancer admitted in our hospital from January 1998 to December 2017 were retrospectively analyzed. ［Results］ Composition ratio of patients aged ＜40 years was decreased from 28.03% in 1998~2007 to 14.17% in 2008~2017(P<0.05)，while those of patients aged 40~60 years and >60 years were increased from 57.50% and 14.47% in 1998~2007 to 66.48% and 19.34% in 2008~2017(P<0.05)，respectively. The rate of epithelial ovarian cancer rose from 72.56% in 1998~2007 to 90.80% in 2008~2017(P <0.05)，while those of germ cell tumor and gonadal stromal cell tumor were decreased from 13.56% and 12.66% in 1998~2007 to 3.83% and 4.79% in 2008~2017(P<0.05). Epithelial ovarian cancer was the major pathological type in patients aged above 40 years，particularly in those aged >60 year-old. The rate of epithelial ovarian cancer in young patients rose from 38.71% in 1998~2007 to 68.92% in 2008~2017(P<0.05). The ovarian cancer was mostly in stage Ⅰ in younger patients. There was an increasing trend of stage Ⅲ ovarian cancer，which was increased from 46.11% in 1998~2007 to 60.34% in 2008~2017(P<0.05). ［Conclusion］ The age group 40 to 60 years is still the main risk population for ovarian cancer. Epithelial ovarian cancer is the main pathological type，especially in the patients aged over 60 years-old，and most patients are in the late stage at the diagnosis. |
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