| 张惠博,宋启斌,于金明.阿帕替尼治疗晚期胃癌的研究进展[J].肿瘤学杂志,2019,25(6):573-576. |
| 阿帕替尼治疗晚期胃癌的研究进展 |
| Research Progress of Apatinib in Treatment of Advanced Gastric Cancer |
| 投稿时间：2018-03-07 |
| DOI：10.11735/j.issn.1671-170X.2019.06.B016 |
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| 中文关键词: 阿帕替尼 胃肿瘤 晚期 靶向治疗 |
| 英文关键词:Apatinib gastric cancer advanced targeted therapy |
| 基金项目: |
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| 摘要点击次数: 1775 |
| 全文下载次数: 631 |
| 中文摘要: |
| 摘 要：我国胃癌发病率和死亡率高居恶性肿瘤第二位，大多数胃癌患者初诊已达进展期，现有的晚期胃癌标准治疗方案其疗效已达瓶颈。阿帕替尼作为我国自主研发的小分子高选择性肿瘤血管生成抑制剂，在晚期胃癌治疗中取得突破性进展。全文对阿帕替尼在晚期胃癌各线治疗的最新研究进展进行综述。 |
| 英文摘要: |
| Abstract：Gastric cancer is the second leading cause of cancer related incidence and mortality in China，and the majority of patients have reached advanced stage at initial diagnosis. The efficacy and prognosis of gastric cancer are still poor despite standard treatment. Apatinib，a small molecular and high selective angiogenesis inhibitor developed in China，has made a breakthrough in the treatment of advanced gastric cancer. In this paper，the recent advances of Apatinib in the treatment of advanced gastric cancer are reviewed. |
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