| 叶 芳.幽门螺杆菌感染与血液系统疾病的相关性研究进展[J].肿瘤学杂志,2019,25(6):552-556. |
| 幽门螺杆菌感染与血液系统疾病的相关性研究进展 |
| Relationship between Helicobacter Pylori Infection and Hematologic System Diseases |
| 投稿时间：2018-10-04 |
| DOI：10.11735/j.issn.1671-170X.2019.06.B012 |
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| 中文关键词: 幽门螺杆菌 缺铁性贫血 巨幼细胞性贫血 特发性血小板减少性紫癜 过敏性紫癜 黏膜相关淋巴组织淋巴瘤 |
| 英文关键词:Helicobacter pylori iron-deficiency anemia megaloblastic anemia idiopathic thrombocytopenic purpura allergic purpura mucosa-associated lymphoid tissue lymphoma |
| 基金项目:北京市朝阳区科技计划项目（CYSF151510;CYSF1812） |
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| 中文摘要: |
| 摘 要：世界人口幽门螺杆菌（Helicobacter pylori，Hp）感染超过50%，是人类最常见的细菌感染。幽门螺杆菌最常感染的部位是消化系统。随着研究的不断深入，除消化系统疾病外，多种血液系统疾病也被证实与Hp感染有关，其中包括缺铁性贫血（iron-deficiency anemia，IDA）、巨幼细胞性贫血（megaloblastic anemia，MA）、特发性血小板减少性紫癜（idiopathic thrombocytopenic purpura，ITP）、过敏性紫癜（allergic purpura，AP）、胃黏膜相关性淋巴组织（mucosa-associated lymphoid tissue，MALT）淋巴瘤等。以上血液系统疾病患者Hp感染率普遍高于正常人，并且在根除Hp后，上述血液系统疾病的临床症状分别得到不同程度的缓解甚至痊愈，提示Hp通过不同机制影响上述血液系统疾病的发生、发展。 |
| 英文摘要: |
| Abstract：Helicobacter pylori infection，which accounts for more than 50% of the world’s population，is the most common bacterial infection in human beings. In addition to the digestive system diseases，with the in-depth study，a variety of hematologic system diseases including Iron-deficiency anemia(IDA)，megaloblastic anemia(MA)，idiopathic thrombocytopenic purpura(ITP)，allergic purpura(AP)，and Mucosa-associated lymphoid tissue(MALT) lymphoma have also been confirmed to be associated with Hp. The Hp positive rate of the patients with the above hematologic system disease is generally higher than the normal person，and the clinical symptoms were relieved and even recovered to different degrees after the eradication of Hp. |
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