焦 武,姚 峰,汪雯洁.Neo-Bioscore评分在乳腺癌新辅助化疗预后评估中的价值[J].肿瘤学杂志,2019,25(5):432-435. |
Neo-Bioscore评分在乳腺癌新辅助化疗预后评估中的价值 |
Neo-Bioscore System in Evaluating Prognosis of Breast Cancer Patients Receiving Neoadjuvant Chemotherapy |
投稿时间:2018-04-16 |
DOI:10.11735/j.issn.1671-170X.2019.05.B011 |
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中文关键词: 乳腺癌 新辅助化疗 预后评价 Neo-Bioscore评分 |
英文关键词:breast cancer neoadjuvant chemotherapy prognosis Neo-Bioscore scoring system |
基金项目:湖北省计生委科研项目(JS-2011019) |
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中文摘要: |
摘 要:[目的] 探讨Neo-Bioscore评分系统对比临床分期系统、病理分期系统以及CPS+EG评分系统在乳腺癌新辅助化疗预后评估的价值。[方法] 收集2010年1月至2017年6月乳腺癌新辅助化疗198例患者资料,随访时间为期5年,分别通过4个不同的分期系统进行预后评估,计算5年总体生存率。 [结果] 全组198例患者5年总生存率为72%;不同病理分期之间生存情况存在较多的交叉(P>0.05),而Neo-Bioscore评分系统变化区间最大(P<0.05)。Neo-Bioscore高分值(>3分)与低分值组(≤3分)组生存率比较差异有统计学意义(χ2=17.353,P<0.05)。[结论] Neo-Bioscore分期系统显示出较好的预后评估价值,能更全面地预测乳腺癌新辅助化疗患者的预后。 |
英文摘要: |
Abstract:[Objective] To assess the application of Neo-Bioscore system in evaluating prognosis of breast cancer patients receiving neoadjuvant chemotherapy. [Methods] One hundred and ninety eight patients with breast cancer received neoadjuvant chemotherapy in Renmin Hospital of Wuhan University from January 2010 to June 2017. Patients were followed-up for 5 years,and the 5-year overall survival rate(OS) was calculated. The prognosis of patients was evaluated with clinical staging system,pathological staging system,CPS+EG scoring system and Neo-Bioscore system. [Results] The 5-year overall survival rate was 72% in these patients. Kaplan-Meier survival curve analysis showed that the Neo-Bioscore system had better prognostic stratification than other three systems. The overall survival was significant difference in high Neo-Bioscore group(>3) and low score group(≤3)(χ2=17.353,P<0.05). [ Conclusion] Neo-Bioscore system shows a better prognostic value to predict the survival of breast cancer patients undergoing neoadjuvant chemotherapy. |
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