| 李健强,刘金石,陈奇勋.可切除非小细胞肺癌患者ABO血型与预后相关性[J].肿瘤学杂志,2019,25(5):409-412. |
| 可切除非小细胞肺癌患者ABO血型与预后相关性 |
| Association Between ABO Blood Types and Prognosis in Patients with Resected Non?鄄small Cell Lung Cancer |
| 投稿时间：2018-12-07 |
| DOI：10.11735/j.issn.1671-170X.2019.05.B006 |
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| 中文关键词: ABO血型 肺癌 预后 |
| 英文关键词:ABO blood types lung cancer prognosis |
| 基金项目: |
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| 中文摘要: |
| 摘 要：［目的］ 探讨可切除的非小细胞肺癌ABO血型与预后之间的相关性。［方法］ 回顾性分析2009年1月至2010年12月行肺癌根治术的非小细胞肺癌患者274例，收集包括血型在内的临床资料并进行生存随访。比较各血型之间5年生存率，并采用Cox比例风险模型进行单因素及多因素生存分析。［结果］ O型患者的5年生存率分别为70.1%，A型为67.2%，B型为39.7%，AB型为56%。与非O型患者相比，O型患者5年生存率更高(P=0.002)。多因素分析提示年龄、病理分期，病理分型以及血型为独立的预后因素。［结论］ ABO血型与可切除的非小细胞肺癌预后具有相关性，可作为一种独立的预后因素。 |
| 英文摘要: |
| Abstract：［Objective］ To explore the association between the ABO blood types and the prognosis in patients with resectabled non-small cell lung cancer(NSCLC). ［Methods］ Clinical data of 274 patients with resectable NSCLC admitted from January 2009 to December 2010 were analyzed retrospectively. The five-year overall survival rates(OS) were compared among patients with various blood types. A Cox proportional hazard model was used for the univariate and multivariate survival analyses. ［Results］ The 5-year overall survival rates were 70.1% for blood O group，67.2% for blood A group，39.7% for blood B group and 56% for blood AB group，respectively. The OS rate of patients with blood O type was higher than those of non-O type patients(P=0.002). Multivariate analysis showed that ABO blood types，age，pathological type and stage were independent prognostic factors for patients with resectable NSCLC. ［Conclusion］ The ABO blood group is related to the prognosis of patients with resectable NSCLC. |
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