| 彭凡禹,何 侠,尹 丽.初治M0鼻咽癌根治性放疗后寡转移的治疗进展[J].肿瘤学杂志,2019,25(2):86-90. |
| 初治M0鼻咽癌根治性放疗后寡转移的治疗进展 |
| Progress in Treatment of Oligometastases after Radical Radiotherapy for Nasopharyngeal Carcinoma with M0 Stage at Diagnoses |
| 投稿时间：2018-10-25 |
| DOI：10.11735/j.issn.1671-170X.2019.02.B003 |
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| 中文关键词: 鼻咽肿瘤 放射疗法 寡转移 |
| 英文关键词:nasopharyngeal neoplasms radiotherapy oligometastases |
| 基金项目:国家自然科学基金(81672989；81702685)；江苏省卫生厅青年医学人才基金(QNRC2016648) |
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| 中文摘要: |
| 摘 要：调强放疗时代，远处转移是鼻咽癌综合治疗后的主要失败模式。寡转移概念的提出，使人们对转移性鼻咽癌的预后有了新的认识。单器官转移或转移灶少于5个的鼻咽癌患者的生存明显优于多器官转移者。手术、立体定向放射治疗、射频消融等局部治疗手段联合全身化疗、靶向治疗、免疫治疗不仅提高了鼻咽癌寡转移灶的局部控制、延长患者生存期，甚至有望治愈疾病。 |
| 英文摘要: |
| Abstract：In the era of intensity-modulated radiotherapy(IMRT)，distant metastasis is the main failure mode after comprehensive treatment of nasopharyngeal carcinoma(NPC). The concept of oligometastases has put forward a new understanding of the prognosis of metastatic nasopharyngeal carcinoma. The survival of patients with isolate or less than 5 organ metastases is significantly better than those with multi-organ metastasis. Surgery，stereotactic body radiotherapy(SBRT)，radiofrequency ablation(RFA) and other local treatments combined with systemic chemotherapy，targeted therapy，immunotherapy not only improve the local control of nasopharyngeal carcinoma oligometastases，prolong the survival of patients，but may also cure the disease. |
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