| 赵轩宇,孔为民,商若天.子宫内膜癌1971年临床分期与FIGO2009年手术病理分期比较[J].肿瘤学杂志,2019,25(1):51-54. |
| 子宫内膜癌1971年临床分期与FIGO2009年手术病理分期比较 |
| Comparison of Clinical Staging and Surgical/Pathological Staging for Endometrial Carcinoma |
| 投稿时间：2017-12-30 |
| DOI：10.11735/j.issn.1671-170X.2019.01.B012 |
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| 中文关键词: 子宫内膜癌 临床分期 手术病理分期 |
| 英文关键词:endometrial carcinoma clinical staging surgical staging |
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| 中文摘要: |
| 摘 要：［目的］ 评价子宫内膜癌全面手术病理分期时代下临床分期的不足及改进点。［方法］ 回顾性分析2000~2010年首都医科大学附属北京妇产医院收治经手术治疗的子宫内膜癌患者的完整病例资料。比较临床分期及手术病理分期差异。［结果］ 与手术病理分期相比，临床分期Ⅰ期误差率为16.15%，临床分期Ⅱ期误差率为82.79%。手术前后组织学分级总误差率为37.19%，术后有11.25%患者危险分层由低危转为高危。生存分析结果显示，临床Ⅰ期5年生存率85.37%，手术病理Ⅰ期5年生存率为93.39%（χ2=10.32，P=0.001) 。临床Ⅱ期5年生存率分别为87.25%，手术病理Ⅱ期5年生存率分别为77.78%，无统计学差异。［结论］ 子宫内膜癌临床分期与手术病理分期误差率较高，推荐将术前MRI及宫腔镜等检查纳入临床分期中以增加术前对病变范围评估的准确性。 |
| 英文摘要: |
| Abstract：［Objective］ To examine the differences between clinical staging and surgical/pathological staging for endometrial carcinoma. ［Methods］ Clinical data of 365 patients with endometrial carcinoma admitted during 2000 to 2010 were retrospectively reviewed. The preoperative diagnosis was made according to FICO(International Federation of Gynecology and Obstetrics) clinical staging criteria(1971) ，and surgical/pathological staging was made according to FICO surgical/pathological staging criteria(2009). The correlating between clinical，surgical staging with the survival outcomes was analyzed. ［Results］ Compared to surgical staging，the inconsistence rate for clinical stage Ⅰ patients was 16.15% and that was 82.79% for clinical stage Ⅱ patients. The misdiagnosis rate of preoperative histological grade was 37.19% and 11.25% cases were upgraded to high-risk endometrial carcinoma after surgery. The 5-year overall survival was lower in the clinical stage Ⅰ patients than that in surgical stage Ⅰ patients（χ2=10.32，P=0.001)，but there was no difference in 5-year overall survival rate between clinical stage Ⅱ and surgical stage Ⅱ patients. ［Conclusion］ The inconsistence rate of endometrial cancer between clinical staging and surgical staging is high. It is recommended that preoperative MRI and hysteroscopy should be included in the clinical staging to increase diagnostic accuracy. |
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