| 中文关键词: miR-31 乳腺癌 靶基因 作用机制 |
| 英文关键词:miR-31 breast cancer target gene mechanism |
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| 中文摘要: |
| 摘 要：乳腺癌是女性最常见的恶性肿瘤，近年来多篇文献报道miRNA可通过特异性结合靶基因，参与调控乳腺癌细胞的迁移、侵袭、转移、凋亡等进程。miR-31因介入乳腺癌侵袭-转移级联活动的多个关键步骤而成为研究热点。全文就miR-31在乳腺癌中研究进展作一综述。 |
| 英文摘要: |
| Abstract：Breast cancer is the most common malignant tumor among women. In recent years，many studies have revealed that miRNAs participate in the regulation of cell migration，invasion，metastasis and apoptosis of breast cancer through sequence-specific binding to the target genes. Because of involvement in multiple steps of the invasion-metastasis cascade，miR-31 becomes a hot area of research in breast cancer. This article reviews the recent progress on the roles of miR-31 in breast cancer. |
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