| 中文关键词: TRIM59 肿瘤 增殖 迁移 |
| 英文关键词:TRIM59 tumor proliferation migration |
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| 中文摘要: |
| 摘 要：TRIM59（tripartite motif-containing 59）是一个新型的TRIM(tripartite motif)家族成员，与多种肿瘤有关。研究显示TRIM59作为癌基因，在肺癌、胃癌、肝癌、结直肠癌等肿瘤中表达上调；而且，TRIM59可通过多种途径促进肿瘤细胞的增殖和迁移。TRIM59有望成为肿瘤诊断和治疗的新靶点。 |
| 英文摘要: |
| Abstract：Tripartite motif-containing59 (TRIM59)，a novel member of the TRIM family，is related to various cancers.TRIM59 has been reported to act as an oncogene，which significantly upregulated in various cancers including lung cancer，gastric cancer，hepatocellular carcinoma and colorectal cancer. In addition，TRIM59 could promote the proliferation and migration of tumors through many pathways. TRIM59 is expected to be a new target for tumor diagnosis and treatment. |
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